European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 1999
Oesophagectomy for carcinoma of the oesophagus and oesophagogastric junction.
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Dalrymple-Hay M J, Evans K B, Lea R E
Аннотация
OBJECTIVE: Oesophageal carcinoma has a poor prognosis; surgical resection remains the only chance of cure but is still associated with a significant morbidity and mortality. The aim of this study was to review the results of one surgeon for oesophageal resection for carcinoma of the oesophagus and oesophagogastric junction over a 23 year period.
METHODS: Between January 1974 and December 1996, 591 patients (408 males; 183 females; mean age 66 years) underwent an oesophageal resection for carcinoma of the oesophagus or oesophagogastric junction.
RESULTS: In hospital mortality was 8.8% (52/591). This has decreased to less than 5% for resections between 1985 and 1996. Non-fatal complications occurred in 21% of patients (123/591). Survival, including in hospital mortality (+/-SEM), was 53.98% (+/-2), 31.77% (+/-2) and 15.3% (+/-2) at 1, 2 and 5 years respectively.
CONCLUSION: Early mortality following oesophageal resection has fallen in recent years. Despite considerable experience, long term survival remains disappointingly low.
METHODS: Between January 1974 and December 1996, 591 patients (408 males; 183 females; mean age 66 years) underwent an oesophageal resection for carcinoma of the oesophagus or oesophagogastric junction.
RESULTS: In hospital mortality was 8.8% (52/591). This has decreased to less than 5% for resections between 1985 and 1996. Non-fatal complications occurred in 21% of patients (123/591). Survival, including in hospital mortality (+/-SEM), was 53.98% (+/-2), 31.77% (+/-2) and 15.3% (+/-2) at 1, 2 and 5 years respectively.
CONCLUSION: Early mortality following oesophageal resection has fallen in recent years. Despite considerable experience, long term survival remains disappointingly low.
Предметные рубрики MeSH
AdenocarcinomaAdultAgedCarcinoma, Squamous CellDisease-Free SurvivalEsophageal NeoplasmsEsophagectomyEsophagogastric JunctionEvaluation Studies as TopicFemaleFollow-Up StudiesHumansMaleMiddle AgedProportional Hazards ModelsRetrospective StudiesStatistics, NonparametricSurvival AnalysisTreatment Outcome