Association of degree of loss aversion and grey matter volume in superior frontal gyrus by voxel-based morphometry.

Loss-aversion behaviors reflect individuals' personal preference bias when they meet uncertainties and measure the potential gains and losses of the uncertain situations before making a decision. Such behaviors are common and well documented in daily life; one example is irrational financial investments. The exact neural mechanisms for these loss-aversion behaviors have been widely discussed. In this study, we explored the neural mechanisms of loss-aversion behaviors by using voxel-based morphometry of brain regions based on two datasets. In the behavioral analysis, the degree of individual behavioral loss aversion was measured. Voxel-based morphometry analysis revealed positive correlations between the degree of individual behavioral loss aversion and grey matter volume in the superior frontal gyrus, which may be crucial neural structures for individual loss-aversion behaviors.