Gematologiia i transfuziologiia · 1990
[Characteristics of lymphocyte populations in the bone marrow and peripheral blood of children with non-T cell acute lymphoblastic leukemia during remission].
Сравнительное исследованиеАннотация на английскомСтатьяНазвание и аннотация: Оригинал на русском
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Lenskaia R V, Chernov V M, Adzhimamudova T S, Koliadina E N, Shevdova E Iu, Iurasov S V
Аннотация
Characteristics of lymphocyte populations in the bone marrow and peripheral blood were comparatively analyzed in children with non-T acute lymphoid leukemia (ALL) during remission, and in the reference group of children with conditionally normal hemopoiesis, as well as with population of lymphocytes obtained from the femur of 22-32-week fetuses. The analysis has shown pronounced changes in the children during remission. The shifts in the structure of lymphocyte population in the bone marrow of children during remission of non-T ALL are considered as compensatory, under conditions of a secondary immunodeficiency due to an abrupt diminution of the absolute number of bone marrow and circulating lymphocytes.