The pathology of vulvar neoplasia.

Current literature on the pathology of vulvar disease continues to focus on vulvar intraepithelial neoplasia, the role of human papillomavirus in vulvar neoplasia, and Paget's disease of the vulva. Of particular concern is an increasing incidence of vulvar intraepithelial neoplasia noted over the past several decades, specifically among younger women. Human papillomavirus has emerged as a major factor in this trend. Furthermore, a more aggressive course may ensue in these young women, requiring diligent follow-up.