Ai zheng = Aizheng = Chinese journal of cancer · 2007
[Prognostic analysis of 116 patients with mucoepidermoid carcinoma of the parotid gland].
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Lu Zeng-Hong, Yang An-Kui, Chen Zhi-Xing, Song Ming, Wei Mao-Wen
Аннотация
BACKGROUND & OBJECTIVE: Mucoepidermoid carcinoma is the most common malignant tumor of the salivary, but mucoepidermoid carcinoma of the parotid gland has seldom been reported. This study was to summarize the clinicopathologic prognostic factors of mucoepidermoid carcinoma of the parotid gland.
METHODS: Clinical data of 116 patients with mucoepidermoid carcinoma of the parotid gland, treated in Cancer Center of Sun Yat-sen University from May 1980 to Dec. 2000, were analyzed with Cox univariate and multivariate models.
RESULTS: The overall 5-, 10-, and 15-year survival rates of the 116 patients were 75.64%, 64.55%, and 60.39%, respectively. Univariate survival analysis showed that 12 factors were prognostic factors of mucoepidermoid carcinoma of the parotid gland, such as age, alcohol drinking, T stage, and so on. Multivariate analysis showed that T stage (P = 0.006, OR > 1), pathologic grade (P < 0.001, OR > 1), and distant metastasis (P < 0.001, OR > 1) were independent prognostic factors of mucoepidermoid carcinoma of the parotid gland.
CONCLUSION: T stage, pathologic grade and distant metastasis are independent prognostic factors of mucoepidermoid carcinoma of the parotid gland.
METHODS: Clinical data of 116 patients with mucoepidermoid carcinoma of the parotid gland, treated in Cancer Center of Sun Yat-sen University from May 1980 to Dec. 2000, were analyzed with Cox univariate and multivariate models.
RESULTS: The overall 5-, 10-, and 15-year survival rates of the 116 patients were 75.64%, 64.55%, and 60.39%, respectively. Univariate survival analysis showed that 12 factors were prognostic factors of mucoepidermoid carcinoma of the parotid gland, such as age, alcohol drinking, T stage, and so on. Multivariate analysis showed that T stage (P = 0.006, OR > 1), pathologic grade (P < 0.001, OR > 1), and distant metastasis (P < 0.001, OR > 1) were independent prognostic factors of mucoepidermoid carcinoma of the parotid gland.
CONCLUSION: T stage, pathologic grade and distant metastasis are independent prognostic factors of mucoepidermoid carcinoma of the parotid gland.
Предметные рубрики MeSH
AdolescentAdultAge FactorsAgedAged, 80 and overAlcohol DrinkingBone NeoplasmsBrain NeoplasmsCarcinoma, MucoepidermoidChildFemaleFollow-Up StudiesHumansLymphatic MetastasisMaleMiddle AgedMultivariate AnalysisNeoplasm StagingParotid GlandParotid NeoplasmsProportional Hazards ModelsSurvival RateYoung Adult