[Infection as a complication of treatment of acute leukemia in children].

AIM: Preventing and successful treatment of infections which are complications during treatment of acute leucosis in children. We analyzed a group of children who were treated at our Clinic in the last five-years period

PATIENTS AND

METHODS

In retrospective study we analyzed children who were treated at our Clinic during last five years. We analysed 56 children, and in 42 of them whole treatment was performed at our Clinic. 14 children were treated for some time in the other European Centers.

RESULTS

We analyzed 56 patients. In 49 (89%) diagnose was ALL (Leucosis lymphatica acuta), and in 7 of them diagnose was AML (Leucosis myeloblastica acuta). The most frequent infections which were complications during treatment of leucosis: were infections of the mouth, infections of the respiratory tract-Pneumonia, sepsis and infections of urinary tract. The most frequent causes of infections were: Candida albicans- mouth, Staphylococcus epidermidis and Seratia marcenscens-sepsis, Escherichia colli-urinary tract.

CONCLUSION

According to our investigation we got conclusion is that infections are great problem in treatment of children with acute Leucemia. Prevention, supportive therapy and care are the most important in struggle with this series complication.