Danish medical journal · 2020
Anastomotic technique is not associated with leakage rate after right hemicolectomy.
Оценочное исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Juvik Anne Fogh, Nielsen Sarah, Tolstrup Mai-Britt, Lykke Jakob, Klein Mads
Аннотация
INTRODUCTION: The present study aimed to evaluate the anastomotic leakage rate in relation to anastomotic technique in right hemicolectomy in a single high-volume centre.
METHODS: This was a retrospective single-centre study of prospectively collected data of patients undergoing right hemicolectomy or ileocecal resection in an acute or elective setting over a seven-year period in a large University Hospital. Anastomotic leakage, anastomotic technique (hand-sewn versus stapled anastomosis) and potential confounders were registered. The possible confounding risk factors were explored by univariate analysis. Any variables with a p value less-than 0.2 after univariate logistic regression analysis were included in a subsequent multivariate logistic regression analysis.
RESULTS: A total of 754 patients had a primary anastomosis performed. In 222 (29%) of the patients, anastomosis was hand-sewn and in 528 (70%) stapled. Overall, 26 patients (3.4%) developed an anastomotic leakage. The anastomotic leakage rate was similar following hand-sewn and stapled anastomoses (3.6% (8/221) versus 3.4% (18/527); p = 0.89). Univariate analyses failed to identify any significant risk factors for anastomotic leakage. A multivariate logistic regression analysis with all mentioned co-variates was performed. None of the included variables were significantly associated with anastomotic leakage.
CONCLUSIONS: In the present study, we found no significant difference between hand-sewn versus stapled anastomosis.
FUNDING: none.
TRIAL REGISTRATION: not relevant.
METHODS: This was a retrospective single-centre study of prospectively collected data of patients undergoing right hemicolectomy or ileocecal resection in an acute or elective setting over a seven-year period in a large University Hospital. Anastomotic leakage, anastomotic technique (hand-sewn versus stapled anastomosis) and potential confounders were registered. The possible confounding risk factors were explored by univariate analysis. Any variables with a p value less-than 0.2 after univariate logistic regression analysis were included in a subsequent multivariate logistic regression analysis.
RESULTS: A total of 754 patients had a primary anastomosis performed. In 222 (29%) of the patients, anastomosis was hand-sewn and in 528 (70%) stapled. Overall, 26 patients (3.4%) developed an anastomotic leakage. The anastomotic leakage rate was similar following hand-sewn and stapled anastomoses (3.6% (8/221) versus 3.4% (18/527); p = 0.89). Univariate analyses failed to identify any significant risk factors for anastomotic leakage. A multivariate logistic regression analysis with all mentioned co-variates was performed. None of the included variables were significantly associated with anastomotic leakage.
CONCLUSIONS: In the present study, we found no significant difference between hand-sewn versus stapled anastomosis.
FUNDING: none.
TRIAL REGISTRATION: not relevant.