Tumori · 2008
Human papillomavirus infection in patients with residual or recurrent cervical intraepithelial neoplasia.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
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Takac Iztok
Аннотация
AIMS AND BACKGROUND: The main purpose of this longitudinal study was to evaluate the frequency of HPV infection in patients with residual or recurrent CIN.
METHODS: 797 consecutive patients with CIN, treated with conization, were included. In 38 patients with residual or recurrent CIN in whom reconization was performed, infection with high-risk HPV types was analyzed.
RESULTS: Reconization was performed in 4.8% of patients. Before reconization, 21 patients (55.3%) were infected with high-risk HPV and 17 patients (44.7%) were HPV negative. Among the HPV-negative patients, two (11.8%) had CIN 1, five (29.4%) CIN 2, nine (52.9%) CIN 3 and one patient (5.9%) had microinvasive cancer of the uterine cervix. The difference in frequency of infection with high-risk HPV was not significant (chi-square 0.372; P > 0.05).
CONCLUSIONS: On the basis of the study results it is not possible to recommend the HPV test as the only method of detection of residual or recurrent CIN after conization.
METHODS: 797 consecutive patients with CIN, treated with conization, were included. In 38 patients with residual or recurrent CIN in whom reconization was performed, infection with high-risk HPV types was analyzed.
RESULTS: Reconization was performed in 4.8% of patients. Before reconization, 21 patients (55.3%) were infected with high-risk HPV and 17 patients (44.7%) were HPV negative. Among the HPV-negative patients, two (11.8%) had CIN 1, five (29.4%) CIN 2, nine (52.9%) CIN 3 and one patient (5.9%) had microinvasive cancer of the uterine cervix. The difference in frequency of infection with high-risk HPV was not significant (chi-square 0.372; P > 0.05).
CONCLUSIONS: On the basis of the study results it is not possible to recommend the HPV test as the only method of detection of residual or recurrent CIN after conization.