The National Project on Achievement in Twins: Integrating Across Data Resources in the United States.

The National Project on Achievement in Twins (NatPAT) is a twin project based in the United States (US) that began in 2017. Using a cohort sequential design, the overall goal of the initial project was to uncover salient factors, including genetic and environmental influences, which contribute to the co-development of reading and math performance during elementary school. In 2022, the focus of NatPAT pivoted towards a new focus on the COVID-19 pandemic's short- and long-term impacts on children's reading achievement. In addition, a genomics data collection began. New enrollment into the registry continues every year, but currently NatPAT follows 1997 twin pairs and their families as they progress through school. The project supports open science principles, with open materials and code, preregistration, and shared data. Here we present the goals of the project, summarize recent results, methods and materials, with a focus on the integration across many different data sources, and future directions of the project.