Larger Blood Volume Increases Detection of Fastidious Mycobacteria and Fungi in Blood Culture.

Blood volume impacts the sensitivity of blood culture for diagnosis of bloodstream infections caused by nonfastidious organisms, but its effect on recovery of fastidious organisms is poorly understood. Collection of 2 Myco/F Lytic bottles, 5 mL of blood each, increased the recovery of fastidious mycobacteria and fungi by 24.1% (7 of 29).