Pediatric endocrinology, diabetes, and metabolism · 2026
Thyroid ultrasonography versus scintigraphy for establishing a stepwise imaging approach in pediatric patients with thyroid dysgenesis in resource-limited settings.
СтатьяСравнительное исследованиеНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Arafa Noha, Atef Shimaa, Elshwimy Nehad Kamal Hamed, Onsy Marwa Mohamed Mohamed, Hassanein Samah Ahmed
Аннотация
INTRODUCTION: Thyroid scintigraphy and ultrasonography are the two primary imaging modalities widely used for thyroid visualization in pediatric patients with congenital hypothyroidism (CH). These modalities provide complementary information. In resource-limited settings, adopting a stepwise approach for selecting the initial imaging modality is essential.
AIM OF THE STUDY: To compare the diagnostic performance of thyroid ultrasonography, thyroid scintigraphy, and combined modalities in categorizing the type of thyroid dysgenesis.
MATERIAL AND METHODS: This cross-sectional study included 56 patients with CH due to thyroid dysgenesis. 99mTc thyroid scintigraphy was performed in all patients at diagnosis. Participants underwent thyroid ultrasonographic examination.
RESULTS: Ultrasonography showed the highest sensitivity in diagnosing thyroid hypoplasia (75%) but lacked sensitivity in detecting ectopic thyroid. Thyroid scintigraphy sensitivity was highest for diagnosing ectopic glands and agenesis (100%) but less sensitive for hypoplasia (54.5%). Combining both imaging modalities demonstrated a sensitivity and accuracy of 100% across all types of dysgenesis.
CONCLUSIONS: Combined thyroid scintigraphy and ultrasonography demonstrated superior diagnostic accuracy, enabling precise characterization of thyroid dysgenesis. If the combined approach is not feasible, initiating thyroid scintigraphy is recommended as the first-line imaging modality and neck ultrasonography serves as a complementary second line imaging technique.
AIM OF THE STUDY: To compare the diagnostic performance of thyroid ultrasonography, thyroid scintigraphy, and combined modalities in categorizing the type of thyroid dysgenesis.
MATERIAL AND METHODS: This cross-sectional study included 56 patients with CH due to thyroid dysgenesis. 99mTc thyroid scintigraphy was performed in all patients at diagnosis. Participants underwent thyroid ultrasonographic examination.
RESULTS: Ultrasonography showed the highest sensitivity in diagnosing thyroid hypoplasia (75%) but lacked sensitivity in detecting ectopic thyroid. Thyroid scintigraphy sensitivity was highest for diagnosing ectopic glands and agenesis (100%) but less sensitive for hypoplasia (54.5%). Combining both imaging modalities demonstrated a sensitivity and accuracy of 100% across all types of dysgenesis.
CONCLUSIONS: Combined thyroid scintigraphy and ultrasonography demonstrated superior diagnostic accuracy, enabling precise characterization of thyroid dysgenesis. If the combined approach is not feasible, initiating thyroid scintigraphy is recommended as the first-line imaging modality and neck ultrasonography serves as a complementary second line imaging technique.