Quintessence international (Berlin, Germany : 1985) · 2026
Clinical performance of resin infiltration and different sealant modalities in noncavitated pits and fissures: a split-mouth randomized controlled trial.
СтатьяРандомизированное исследованиеСравнительное исследованиеНазвание и аннотация: Перевод пока не подготовлен
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Solanki Jyoti, Jindal Garima, Ansari Afroz Alam, Singh Rajeev Kumar, Khanna Richa
Аннотация
OBJECTIVE: To compare the clinical performance of resin infiltration and different pit and fissure sealants in young permanent molars.
METHOD AND MATERIALS: This split-mouth randomized controlled trial evaluated 128 permanent molars with noncavitated occlusal lesions (ICDAS 0-2) in 32 children aged 7 to 14 years. Teeth were randomly allocated to four groups (n = 32 per group): resin infiltration (Group A), moisture-tolerant resin sealant (Group B), flowable nanohybrid composite (Group C), and a combination of group A and C (Group D). Outcomes assessed were ICDAS scores, DIAGNOdent values, marginal integrity, marginal discoloration, and retention at baseline, 6, and 12 months using generalized estimating equations (GEE) (P .05).
RESULTS: Significant reduction or stabilization in ICDAS scores occurred over time across all groups (P .001). Group A demonstrated significantly higher likelihood of ICDAS stabilization than Group C (OR 1.85; 95% CI 1.10-3.12; P = .021). Group D showed significantly lower lesion progression than Group B (OR 1.72; 95% CI 1.05-2.95; P = .034). At 12 months, retention was high, with only six teeth requiring revision (Group A, n = 1; Group B, n = 2; Group C, n = 3; Group D, n = 0). No significant intergroup differences in DIAGNOdent values or marginal integrity were observed (P > .05).
CONCLUSION: All four evaluated modalities demonstrated significant short-term cariostatic activity. Infiltration-based approaches, particularly the combination approach, demonstrated superior clinical performance by yielding minimal lesion progression, high retention rates, and the lowest incidence of clinical revision in high-caries-risk children.
METHOD AND MATERIALS: This split-mouth randomized controlled trial evaluated 128 permanent molars with noncavitated occlusal lesions (ICDAS 0-2) in 32 children aged 7 to 14 years. Teeth were randomly allocated to four groups (n = 32 per group): resin infiltration (Group A), moisture-tolerant resin sealant (Group B), flowable nanohybrid composite (Group C), and a combination of group A and C (Group D). Outcomes assessed were ICDAS scores, DIAGNOdent values, marginal integrity, marginal discoloration, and retention at baseline, 6, and 12 months using generalized estimating equations (GEE) (P .05).
RESULTS: Significant reduction or stabilization in ICDAS scores occurred over time across all groups (P .001). Group A demonstrated significantly higher likelihood of ICDAS stabilization than Group C (OR 1.85; 95% CI 1.10-3.12; P = .021). Group D showed significantly lower lesion progression than Group B (OR 1.72; 95% CI 1.05-2.95; P = .034). At 12 months, retention was high, with only six teeth requiring revision (Group A, n = 1; Group B, n = 2; Group C, n = 3; Group D, n = 0). No significant intergroup differences in DIAGNOdent values or marginal integrity were observed (P > .05).
CONCLUSION: All four evaluated modalities demonstrated significant short-term cariostatic activity. Infiltration-based approaches, particularly the combination approach, demonstrated superior clinical performance by yielding minimal lesion progression, high retention rates, and the lowest incidence of clinical revision in high-caries-risk children.