American journal of otolaryngology · 2026
Diagnostic accuracy of a thyrothymic ligament-based nomenclature for ultrasound classification of inferior parathyroid gland location.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Yao Xiang-Yun, Liu Shi-Rong, Ge Xi-Feng, Song Shi-Bing, Li Xin
Аннотация
BACKGROUND: Preoperative knowledge of inferior parathyroid gland (IPTG) location and vascular supply is critical for in situ preservation, yet evidence on imaging accuracy for IPTG localization remains limited.
OBJECTIVE: To evaluate the diagnostic accuracy of an ultrasound classification system for IPTG location guided by the thyrothymic ligament (TTL).
METHODS: This prospective, single-center study enrolled consecutive patients scheduled for thyroidectomy from January 2025 to September 2025. The reference standard was surgical exploration confirmed by negative mitoxantrone hydrochloride staining or frozen section pathology. Concordance between ultrasound localization and surgical findings was assessed, and factors influencing accuracy were analyzed.
RESULTS: Among the 158 patients (123 lobectomies and 35 total thyroidectomies, 193 IPTG sides), the TTL was clearly identified intraoperatively in 47.7% (92/193). Ultrasound sensitivity, specificity and accuracy for TTL identification were 94.6% (87/92), 84.2% (85/101) and 89.1% (172/193), respectively. IPTG locations were classified as: dorsal mid-to-lower thyroid (35.2%), within 1 cm of the inferior thyroid pole (13.5%), within the TTL region (43.0%), and ectopic (8.3%). Overall concordance between ultrasound classification and surgical exploration was 81.3% (157/193, 95%CI: 74.6%-86.6%). IPTG within the TTL region (OR = 7.64, 95%CI: 1.22-47.93, P = 0.03) and ectopic IPTG (OR = 0.06, 95%CI: 0.01-0.27, P < 0.01) were independent predictors of ultrasound accuracy.
CONCLUSION: Ultrasound-based TTL identification provides a reproducible and reliable method for classifying IPTG location, which may aid in developing individualized surgical strategies for parathyroid preservation during thyroidectomy.
OBJECTIVE: To evaluate the diagnostic accuracy of an ultrasound classification system for IPTG location guided by the thyrothymic ligament (TTL).
METHODS: This prospective, single-center study enrolled consecutive patients scheduled for thyroidectomy from January 2025 to September 2025. The reference standard was surgical exploration confirmed by negative mitoxantrone hydrochloride staining or frozen section pathology. Concordance between ultrasound localization and surgical findings was assessed, and factors influencing accuracy were analyzed.
RESULTS: Among the 158 patients (123 lobectomies and 35 total thyroidectomies, 193 IPTG sides), the TTL was clearly identified intraoperatively in 47.7% (92/193). Ultrasound sensitivity, specificity and accuracy for TTL identification were 94.6% (87/92), 84.2% (85/101) and 89.1% (172/193), respectively. IPTG locations were classified as: dorsal mid-to-lower thyroid (35.2%), within 1 cm of the inferior thyroid pole (13.5%), within the TTL region (43.0%), and ectopic (8.3%). Overall concordance between ultrasound classification and surgical exploration was 81.3% (157/193, 95%CI: 74.6%-86.6%). IPTG within the TTL region (OR = 7.64, 95%CI: 1.22-47.93, P = 0.03) and ectopic IPTG (OR = 0.06, 95%CI: 0.01-0.27, P < 0.01) were independent predictors of ultrasound accuracy.
CONCLUSION: Ultrasound-based TTL identification provides a reproducible and reliable method for classifying IPTG location, which may aid in developing individualized surgical strategies for parathyroid preservation during thyroidectomy.