Blepharochalasis syndrome: a proposed pathophysiologic mechanism.

The blepharochalasis syndrome is an uncommon disorder seen in young people that is characterized by recurrent episodes of eyelid edema. After repeated episodes various eyelid supportive structures are stretched, giving rise to the characteristic features of thin excess lid skin, blepharoptosis, pseudoepicanthal folds, and disinserted lateral canthal tendons. Surgical repositioning and reconstruction are often required. The author describes 10 patients with this disorder and suggests a relation to angioedema, a common dermatologic condition with numerous triggering mechanisms.