Pediatric surgery international · 2025
Single-stage laparoscopic proctocolectomy with ileal pouch-anal anastomosis for familial adenomatous polyposis.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Mudreac Andrew, Kim Spencer E, Kennedy Kara, Johnston William R, Hwang Rosa, Mattei Peter
Аннотация
PURPOSE: Assess the safety of single-stage laparoscopic proctocolectomy with ileal pouch-anal anastomosis (LPC-IPAA) in children with familial adenomatous polyposis (FAP).
METHODS: Medical records for all patients with FAP who underwent LPC-IPAA between 1/1/2013 and 8/1/2024 at a pediatric center were reviewed. Baseline characteristics, postoperative complications, and functional outcomes were assessed.
RESULTS: Thirty-nine patients met inclusion criteria. Mean age was 14.9 years (range 9.4-21.5) and mean BMI was 23.0 (range 15.3-47.0). Follow-up averaged 2.8 years (SD 2.9). Mean operative time was 228.4 min (SD 44.5) in the stapled group (n = 32) and 316.1 min (SD 43.1) in the hand-sewn group (n = 7) (p < 0.001). There were no anastomotic leaks. One patient developed a postoperative abscess. Six (15%) developed presumed pouchitis, 4 of whom were in the hand-sewn group and all successfully treated with antibiotics. Six patients (15%) developed an anastomotic stricture - all in the stapled group - and responded well to anal dilation. No patient required treatment for fecal incontinence.
CONCLUSION: LPC-IPAA in adolescents and young adults with FAP can safely be performed in a single operation and is associated with favorable functional outcomes.
METHODS: Medical records for all patients with FAP who underwent LPC-IPAA between 1/1/2013 and 8/1/2024 at a pediatric center were reviewed. Baseline characteristics, postoperative complications, and functional outcomes were assessed.
RESULTS: Thirty-nine patients met inclusion criteria. Mean age was 14.9 years (range 9.4-21.5) and mean BMI was 23.0 (range 15.3-47.0). Follow-up averaged 2.8 years (SD 2.9). Mean operative time was 228.4 min (SD 44.5) in the stapled group (n = 32) and 316.1 min (SD 43.1) in the hand-sewn group (n = 7) (p < 0.001). There were no anastomotic leaks. One patient developed a postoperative abscess. Six (15%) developed presumed pouchitis, 4 of whom were in the hand-sewn group and all successfully treated with antibiotics. Six patients (15%) developed an anastomotic stricture - all in the stapled group - and responded well to anal dilation. No patient required treatment for fecal incontinence.
CONCLUSION: LPC-IPAA in adolescents and young adults with FAP can safely be performed in a single operation and is associated with favorable functional outcomes.