Peripheral venous thrombosis in children and adolescents with adipsic hypernatremia secondary to hypothalamic tumors.

OBJECTIVE

To determine the clinical presentation and laboratory follow-up in patients with the syndrome of adipsic hypernatremia complicated with a peripheral thrombosis event.

METHODS

Report of 3 patients (6-19 years old) with chronic hypernatremia with sustained difficulties to normalize their serum osmolality levels.

RESULTS

During post-surgical management the 3 patients developed a peripheral venous thrombotic event as a complication of their chronic hyperosmolality.

CONCLUSIONS

Chronic hypernatremia in patients with prolonged immobilization is associated with an increased risk for development of deep venous thrombosis.