[Sertraline hydrochloride combined with compound chamomile lidocaine gel for the treatment of premature ejaculation].

OBJECTIVE

To investigate the effect of sertraline hydrochloride combined with compound chamomile lidocaine gel in the treatment of premature ejaculation (PE).

METHODS

We selected 80 cases of PE treated in our hospital from June 2021 to May 2023 and equally randomized them into a control and an observation group, the former medicated with compound chamomile lidocaine gel while the latter with sertraline hydrochloride in addition, both for 6 weeks. We recorded and compared the intravaginal ejaculation latency time (IELT), the number of successful sexual intercourses per week, the Premature Ejaculation Diagnostic Tool (PEDT) scores, and the incidence of adverse reactions between the two groups of patients.

RESULTS

After the treatment, the IELT was significantly longer (［5.39 ± 1.17］ vs ［2.49 ± 0.73］ min, P< 0.05), the weekly number of successful sexual intercourses remarkably higher (1.82 ± 0.45 vs 0.93 ± 0.19, P< 0.05) and the PEDT scores markedly lower (7.42 ± 2.04 vs 9.85 ± 2.36, P< 0.05) in the observation than in the control group, but no statistically significant differences were observed in the baseline PEDT scores or the incidence of adverse reactions between the two groups (P> 0.05).

CONCLUSION

Sertraline hydrochloride combined with compound chamomile lidocaine gel is definitely effective in the treatment of PE, which can significantly improve the patients' quality of sexual life, with a high safety and low incidence of adverse reactions.