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Войти в исследования Head & face medicine · 2025
Application value of indocyanine green lymphography in the management of stage I/IIA microcystic lymphatic malformation of the tongue.
СтатьяРандомизированное исследованиеНазвание и аннотация: Перевод в очереди
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Han Tao, Shi Lijun, Huang Songming, Shen Weimin
Аннотация
BACKGROUND: This study aims to investigate whether indocyanine green lymphography (ICGL) facilitates the effectiveness and accuracy of current management of lingual microcystic lymphatic malformation (mLM).
METHODS: This retrospective included patients under 18 years old with mLM of the tongue staged I or IIA, who underwent ICGL-aided surgical resection and sclerotherapy (ICGL group) or only surgical resection and sclerotherapy (non-ICGL group) between January 2019 and June 2024. The peri- and postoperative parameters of safety and feasibility were compared between two groups.
RESULTS: A total of 42 patients were included, 19 of whom received ICGL-guidance and the other 23 were in non-ICGL group. The comparison of baseline data between the two groups revealed no significant difference. Compared to the non-ICGL group, the ICGL group demonstrated superior efficacy (P = 0.017) and required fewer subsequent treatment sessions (P = 0.027), but had longer operative duration (P = 0.001). No significant differences were observed in terms of postoperative complications, length of hospital-stay, and follow-up period.
CONCLUSIONS: ICGL was associated with improved postoperative outcomes and less subsequent treatment. This technique may provide rational guidance with promising clinical prospects for management of mLM of the tongue.
TRAIL REGISTRATION: This study was retrospectively registered on clinicaltrials.gov: NCT06755905, date of registration: January 20, 2025.
METHODS: This retrospective included patients under 18 years old with mLM of the tongue staged I or IIA, who underwent ICGL-aided surgical resection and sclerotherapy (ICGL group) or only surgical resection and sclerotherapy (non-ICGL group) between January 2019 and June 2024. The peri- and postoperative parameters of safety and feasibility were compared between two groups.
RESULTS: A total of 42 patients were included, 19 of whom received ICGL-guidance and the other 23 were in non-ICGL group. The comparison of baseline data between the two groups revealed no significant difference. Compared to the non-ICGL group, the ICGL group demonstrated superior efficacy (P = 0.017) and required fewer subsequent treatment sessions (P = 0.027), but had longer operative duration (P = 0.001). No significant differences were observed in terms of postoperative complications, length of hospital-stay, and follow-up period.
CONCLUSIONS: ICGL was associated with improved postoperative outcomes and less subsequent treatment. This technique may provide rational guidance with promising clinical prospects for management of mLM of the tongue.
TRAIL REGISTRATION: This study was retrospectively registered on clinicaltrials.gov: NCT06755905, date of registration: January 20, 2025.