British journal of haematology · 2003
Burkitt's and Burkitt-like lymphoma in children and adolescents: a review of the Children's Cancer Group experience.
Клиническое исследованиеСтатьяМногоцентровое исследованиеРандомизированное исследованиеПоддержка исследования: вне правительства СШАПоддержка правительства СШАПоддержка службы здравоохранения СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Cairo Mitchell S, Sposto Richard, Perkins Sherrie L, Meadows Anna T, Hoover-Regan Margo L, Anderson James R, Siegel Stuart E, Lones Mark A, Tedeschi-Blok Nicole, Kadin Marshall E, Kjeldsberg Carl R, Wilson John F, Sanger Warren, Morris Erin, Krailo Mark D, Finlay Jonathan L
Аннотация
OBJECTIVES: Fracture events due to osteoporosis (OP) are a major health burden in an ageing population. Their diagnosis and treatment provides the opportunity to prevent further fractures. However, the identification and treatment of underlying OP is often unsatisfactory. This longitudinal observational study, attempts to understand the barriers hindering OP treatment initiation in patients entering our hospital for fragility fracture.
METHODS: 349 patients with fragility fracture underwent OP education (interview with a trained nurse) and were offered further OP care either with their general physician (or private rheumatologist) or at the hospital. In the latter case, the patients were given an appointment for OP-centred investigation and consultation. Six months after the fracture they were contacted to know whether they had been investigated and had started a treatment for OP (outcome). The factors predicting the outcome were analysed.
RESULTS: The organisation of further OP care at the hospital yielded the highest probability of being treated (OR 118.09; 95%CI [13.93-1000.92]), while patient's education on OP had a slighter effect (OR 4.74; 95%CI [2.15-10.44]). A low social status was the strongest patient-related negative predictor of further treatment (OR 0.22 [95%CI 0.09-0.47]).
CONCLUSIONS: The organisation of patients' OP care is the strongest determinant of OP investigation and treatment after fracture, and this aspect should be considered when attempting to increase OP care in everyday practice. Patients having a low social status are less likely to be investigated and treated, and additional efforts to properly organise their care are warranted.
METHODS: 349 patients with fragility fracture underwent OP education (interview with a trained nurse) and were offered further OP care either with their general physician (or private rheumatologist) or at the hospital. In the latter case, the patients were given an appointment for OP-centred investigation and consultation. Six months after the fracture they were contacted to know whether they had been investigated and had started a treatment for OP (outcome). The factors predicting the outcome were analysed.
RESULTS: The organisation of further OP care at the hospital yielded the highest probability of being treated (OR 118.09; 95%CI [13.93-1000.92]), while patient's education on OP had a slighter effect (OR 4.74; 95%CI [2.15-10.44]). A low social status was the strongest patient-related negative predictor of further treatment (OR 0.22 [95%CI 0.09-0.47]).
CONCLUSIONS: The organisation of patients' OP care is the strongest determinant of OP investigation and treatment after fracture, and this aspect should be considered when attempting to increase OP care in everyday practice. Patients having a low social status are less likely to be investigated and treated, and additional efforts to properly organise their care are warranted.
Предметные рубрики MeSH
AdolescentAdultAge FactorsAntineoplastic Combined Chemotherapy ProtocolsBiomarkers, TumorBone MarrowBurkitt LymphomaCentral Nervous SystemChildChild, PreschoolDisease-Free SurvivalFemaleHumansInfantInfant, NewbornL-Lactate DehydrogenaseMaleMultivariate AnalysisPrognosisProportional Hazards ModelsRandomized Controlled Trials as TopicSurvival RateTreatment Outcome