International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2026
Parental vaccination status and other socioeconomic determinants shaping COVID-19 vaccine uptake in children and adolescents in Singapore.
СтатьяНазвание и аннотация: Перевод в очереди
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Ngiam Jinghao Nicholas, Yap Alex J W, Wee Liang En, Koh Matthew Chung Yi, Lim Soon Kok, Lim Jue Tao, Chiew Calvin J, Li Russell Jingxian, Lee Vernon, Lye David Chien Boon, Tan Kelvin Bryan
Аннотация
OBJECTIVES: During the pandemic, achieving high and equitable COVID-19 vaccination coverage in children and adolescents was essential for reducing transmission, protecting vulnerable household members, and limiting disruption to schools. We examined real-world uptake of COVID-19 vaccine doses among children and adolescents in Singapore, where vaccinations for those aged 12-17 years and 5-11 years were introduced during the Delta and Omicron waves, respectively.
METHODS: We conducted a retrospective cohort study using national-level data for all children and adolescents aged 5-17 years eligible for vaccination between June 1, 2021, and April 30, 2022. Time-to-vaccination for each dose was analyzed, stratified by age group.
RESULTS: Among 442,399 children and adolescents, uptake declined progressively with each additional vaccination dose. Among adolescents aged 12-17 years, 95.8% completed primary vaccination, 92.5% received a first booster, and 18.6% received a second booster. Corresponding uptake among children aged 5-11 years was 75.8%, 46.1%, and 20.2%, respectively. Parental COVID-19 vaccination status was the strongest predictor of uptake. Regular influenza re-vaccination was consistently associated with shorter time-to-vaccination and showed stronger association with booster vaccination.
CONCLUSION: Vaccination uptake was shaped by socioeconomic status, household structure, and parental vaccination. Tailored, family-centered strategies may help support rollout of vaccination programs.
METHODS: We conducted a retrospective cohort study using national-level data for all children and adolescents aged 5-17 years eligible for vaccination between June 1, 2021, and April 30, 2022. Time-to-vaccination for each dose was analyzed, stratified by age group.
RESULTS: Among 442,399 children and adolescents, uptake declined progressively with each additional vaccination dose. Among adolescents aged 12-17 years, 95.8% completed primary vaccination, 92.5% received a first booster, and 18.6% received a second booster. Corresponding uptake among children aged 5-11 years was 75.8%, 46.1%, and 20.2%, respectively. Parental COVID-19 vaccination status was the strongest predictor of uptake. Regular influenza re-vaccination was consistently associated with shorter time-to-vaccination and showed stronger association with booster vaccination.
CONCLUSION: Vaccination uptake was shaped by socioeconomic status, household structure, and parental vaccination. Tailored, family-centered strategies may help support rollout of vaccination programs.