Journal of surgical oncology · 2025
What Are the Long-Term Clinical and Functional Outcomes After Hemicortical Allograft Reconstruction for Primary Bone Tumors?
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Gonzalez Marcos R, Okay Erhan, Werenski Joseph O, Connolly Joseph J, Pfeiffer Andrew, Newman Erik T, Raskin Kevin A, Lozano-Calderón Santiago A
Аннотация
BACKGROUND: Hemicortical allograft reconstruction is associated with low short-term complication rates and excellent functional outcomes. However, data on their long-term complication profile and patient-reported outcomes is scarce to non-existent.
METHODS: Patients with hemicortical resection and allograft reconstruction for primary bone tumors were included. The Henderson classification for biologic reconstruction was used to classify allograft failures. Functional outcomes at a minimum of 10 years postoperatively were assessed.
RESULTS: Twenty-four patients with femur hemicortical allograft and 20 with tibia allograft were included. Allograft failure and reoperation occurred in 39% and 52% of patients, respectively. The main causes of allograft failure were infection, soft-tissue failure, and structural failure (9% each). Tibia allografts had a higher rate of failure due to infection (p = 0.02) and nonunion (p = 0.049) compared to femur allografts. There were no differences in allograft failure-free survival based on bone (tibia vs. femur) and osteosynthesis type (plate vs. screw and plates). Median TESS-LE and LEFS scores were 98.8% and 87.5% for tibia allografts, and 98.1% and 97.5% for femur allografts, respectively.
CONCLUSION: Long-term allograft failure-free survival was excellent, with infection and soft-tissue failures as the main failure mechanisms. At last follow-up, patients who still had the hemicortical allograft displayed excellent functional outcomes.
LEVEL OF EVIDENCE: Level IV.
METHODS: Patients with hemicortical resection and allograft reconstruction for primary bone tumors were included. The Henderson classification for biologic reconstruction was used to classify allograft failures. Functional outcomes at a minimum of 10 years postoperatively were assessed.
RESULTS: Twenty-four patients with femur hemicortical allograft and 20 with tibia allograft were included. Allograft failure and reoperation occurred in 39% and 52% of patients, respectively. The main causes of allograft failure were infection, soft-tissue failure, and structural failure (9% each). Tibia allografts had a higher rate of failure due to infection (p = 0.02) and nonunion (p = 0.049) compared to femur allografts. There were no differences in allograft failure-free survival based on bone (tibia vs. femur) and osteosynthesis type (plate vs. screw and plates). Median TESS-LE and LEFS scores were 98.8% and 87.5% for tibia allografts, and 98.1% and 97.5% for femur allografts, respectively.
CONCLUSION: Long-term allograft failure-free survival was excellent, with infection and soft-tissue failures as the main failure mechanisms. At last follow-up, patients who still had the hemicortical allograft displayed excellent functional outcomes.
LEVEL OF EVIDENCE: Level IV.