[Histopathological diagnosis of intestinal motility disorders: Hirschsprung disease and differential diagnoses].

Hirschsprung disease/aganglionosis of the colon is the most common form of intestinal motility disorder, especially in children. In this review article, which was presented at the specialist meeting of the German Paediatric Pathology Working Group, insight into the histopathological diagnosis of Hirschsprung's disease, including the technical approach to biopsies, will be provided. In addition, differential diagnoses of chronic intestinal pseudo-obstruction (CIPO), which can be identified with the help of histopathological diagnostics, are presented. These include-among others-hypoganglionosis, intestinal neuronal dysplasia, ganglionitis, and leiomyositis.