Real-World Performance of Aspergillus and Mucorales Polymerase Chain Reaction Assays on Bronchoalveolar Lavage Fluid in Immunocompromised Children and Young Adults.

We describe use of Aspergillus and Mucorales polymerase chain reaction (PCRs) in 54 immunocompromised children and young adults undergoing 66 bronchoscopies. Test positivity was 2/54 (3.2%) and 1/59 (1.7%) for Aspergillus and Mucorales. For Aspergillus PCRs, 4/54 (7.4%) positively impacted management, compared to 4/59 (6.8%) for Mucorales. Fungal PCRs may influence care of immunocompromised patients, though overall impact was limited.