Management of Hypertension and Associated Comorbidities: An Expert Consensus Statement from India.

Hypertension is a leading global health concern that significantly contributes to cardiovascular (CV) and renal diseases. In India, its prevalence is rising, often coexisting with comorbidities such as type 2 diabetes mellitus (T2DM), chronic kidney disease (CKD), coronary artery disease (CAD), and metabolic syndrome (MetS). Effective hypertension management in these populations is challenging due to variations in blood pressure (BP) targets, the need for combination therapy, and the complexity of treating associated conditions such as albuminuria, nephropathy, CKD, CAD, and acute coronary syndromes (ACS). Despite advancements in treatment options, inconsistencies in clinical practice highlight the need for standardized, evidence-based recommendations. This expert consensus aims to address these gaps by guiding BP targets, optimal antihypertensive strategies, and individualized treatment approaches for high-risk patients. Key considerations include the role of renin-angiotensin-aldosterone system blockers, calcium channel blockers (CCBs), beta-blockers (BBs), sodium-glucose cotransporter-2 inhibitors, and combination therapies in improving CV and renal outcomes. By establishing clear, consensus-driven recommendations, this statement seeks to enhance hypertension management, promote early intervention, and improve patient outcomes in India.