Management of Pediatric Acne Vulgaris and Hidradenitis Suppurativa in Minoritized and Underserved Populations.

This article provides guidance on the management of acne vulgaris (AV) and hidradenitis suppurativa (HS) in youth with skin of color (SOC) and youth who are transgender and gender diverse (TGD). Both diseases are associated with delayed diagnosis, treatment disparities, and heightened psychosocial burdens in underrepresented groups. For children with SOC and AV, it is crucial to minimize the risk of postinflammatory hyperpigmentation, with recommendations for starting lower concentrations of retinoids and cautious selection of oral therapies. In children who are TGD, masculinizing hormone therapy for transmasculine individuals may exacerbate acne, necessitating careful treatment planning. In HS, early and aggressive therapy is essential to prevent disease progression and scarring. While biologic agents (eg, adalimumab) demonstrate efficacy, they are underutilized in adolescents. Treatment adherence in both AV and HS can be influenced by systemic barriers to care, highlighting the need for culturally sensitive, multi-disciplinary approaches that address both the dermatologic and psychosocial aspects of care. [Pediatr Ann. 2025;54(6):e209-e216.].