[The level of endothelin-1 in blood serum and nasal secretion of patients presenting with chronic rhinitis].

The level of endothelin-1 (ET-1) in blood serum and nasal secretion was simultaneously determine by the relevant immunoenzyme assay in 23 of patients presenting with chronic rhinitis and in12 healthy subjects. It was shown that both vasomotor and chronic hypertrophic rhinitides are characterized by a similar (two-fold) rise in the serum ET-1 concentration. The six-fold increase of the ET-1 level in nasal secretion in chronic hypertrophic rhinitis compared with the respective normal parameter exceeds that in the vasomotor form of this pathology.