Prevalence and risk of developing comorbid conditions in patients with chronic constipation.
OBJECTIVE: To estimate the prevalence of gastrointestinal (GI) and non-GI comorbidities and the risk of incident comorbidities among patients with and without chronic constipation (CC). RESEARCH DESIGN AND METHODS: Adults with CC were identified from a large retrospective US claims database. Each CC patient was matched 1:3 to CC-free patients by birth year, sex, and region of residence. MAIN OUTCOME MEASURES: Prevalence of GI and non-GI comorbidities was measured over a 1-year period. Relative risk of new comorbidities was also estimated among patients who were free of the studied comorbidit
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