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Third cranial nerve palsy caused by gummatous neurosyphilis: MR findings.

The clinical and MR findings in an unusual case of gummatous neurosyphilis are reported. A 44-year-old woman suffering from diplopia and right-sided headaches was admitted. Physical examination and routine laboratory parameters were normal except for a third-nerve palsy. MR images revealed a contrast-enhancing lesion of the upper brain stem and third cranial nerve. Differential diagnosis included neuroma of the third cranial nerve, as well as neurosarcoidosis and other inflammatory processes. Serologic tests and lumbar puncture revealed the presence of active syphilis. After intravenous treatm…

Neurosyphilis with associated retinitis.

A 59-year-old black male presented with an acute unilateral central scotoma and decreased visual acuity in each eye. Ocular examination revealed bilateral vitritis, nerve fiber layer hemorrhages and infarcts, arteritis, serous macular edema and optic nerve head edema with telangiectasia. Vascular work-up was remarkable for a reactive FTA-ABS, VDRL and RPR. Lymphocytes, monocytes, basophils and platelet count were elevated. HIV tests were nonreactive. Ocular, serologic and cerebrospinal fluid findings along with past sexual history were consistent with a diagnosis of early neurosyphilis. Prompt

[Kidney failure, acute hepatitis and rhabdomyolysis secondary to an acute cytomegalovirus infection in a previously healthy patient].

A 40-year-old male with unremarkable past history was admitted because of fainting during an athletic run in the city. At the time of admission there were increased plasma creatinine level and phosphokinase activity, with myoglobinuria and increased transaminase activity. Serologic tests for viruses on admission and after 15 days showed a selective increase in the anti-CMV titer from 1/16 to 1/256, being negative for the remaining viruses. The renal function rapidly recovered without sequelae. According to the literature, this would be the first reported case of acute renal failure, rhabdomyol…

[Agar gel microdiffusion reaction in the serologic diagnosis of paracoccidioidomycosis].

We used the micro- and macroimmunodiffusion test for the qualitative and quantitative measurement of anti--P. brasiliensis antibodies in serum of patients with paracoccidioidomycosis. All 103 paracoccidioidomycosis sera (100%) were positive in the microtest versus 87% positivity index in the macrotest. All 83 control sera from patients with other diseases were negative in both tests. Titers of the positive sera tended to be higher in the microtest, which revealed sharper and easier to read precipiting bands. Microimmunodiffusion is simple to be performed, requires a minimum amount of reagents

Tropical medicine and the acute abdomen.

In conclusion, the most important task in evaluating an immigrant or traveler with abdominal pain is to consider the myriad tropical disease … y indicate a need for judicious delay in exploratory laparotomy. In this interval, imaging studies, serologic tests, and therapeutic drug trials may clarify the diagnosis.

Otosyphilis: a practical guide to diagnosis and treatment.

The diagnosis and management of patients with suspected treponemal infection of the temporal bone pose some challenges. The following points deserve emphasis: 1) the MHA-TP or FTA-Abs is recommended over the reagin serologic tests (VDRL, RPR); 2) one should regard this process as an attempt to define a subgroup of patients with sensorineural hearing loss who will benefit from a combination of antibiotics and steroid therapy rather than explicitly diagnosing infection of the temporal bone. The response rate to therapy is limited; but, otosyphilis, as one of the few treatable causes of sensorine…

Quiescent Q fever endocarditis exacerbated by cardiac surgery and corticosteroid therapy.

Q fever endocarditis occurs in up to 11% of patients infected by Coxiella burnetti. Major clues for the diagnosis are culture-negative endocarditis, hepatic involvement, rash, and thrombocytopenia. Characteristically, the diagnosis is delayed. In our patient, Q fever endocarditis occurred without previously recorded signs of infection. Fever, rash, and hepatic involvement all occurred following aortic valve replacement. The histologic picture of the excised valve was consistent with endocarditis, and serologic tests disclosed elevated IgA and IgG antiphase 1 antibody titers against C burnetti,…

[Trichinellosis with neurological complications. Case report and short overview].

A 53-year-old, previously healthy man developed persistent diarrhea 4 days after ingestion of smoked but uncooked pork sausages in the Southern Tyrol. On his return to Switzerland he ate the same sausages and was admitted to hospital with migrating muscle pain, fever and chills. While fever and diarrhea soon regressed, the patient exhibited neurologic symptoms and change of character. The leukocyte count was 14 000/mm3 with 39% eosinophils. 40 days after hospitalization a second muscle biopsy established the diagnosis of Trichinella spiralis infection. At the same time, serologic tests were po…

Клинические представления о лихорадке Рокки Маунтин. Комментарии по вопросам распознавания и управления, основанные на исследовании 63 пациентов.

В Соединенных Штатах продолжает расти пятнистая лихорадка Рокки Маунтин, и соотношение числа случаев заболевания остается неизменным, несмотря на наличие эффективных антибиотиков. Очевидной причиной сохраняющейся смертности от этого заболевания является неспособность врачей рассмотреть диагноз пациентов с фебриальными экантемами в конце весны и лета. Клиническая диагностика должна основываться на истории воздействия клещей и на наличии лихорадки и типичного экантема. Серологические тесты полезны главным образом в ретроспективе. В этой статье дается обзор клинического опыта, связанного с лихора

Совпадение в аннотации оригинала
Rocky Mountain spotted fever continues to increase in the United States and the case-fatality ratio remains unchanged despite the availabili … should be based on the history of tick exposure and the presence of fever and the typical exanthem. Serologic tests are useful mainly in retrospect. This article reviews the clinical experience with Rocky Mountain spotted fever in an endemic area in recent years and discusses problems in the diagnosis and management.

Helicobacter pylori "test-and-scope" strategy for dyspeptic patients. Is it useful and safe?

AIM: To evaluate outcome of test-and-scope strategy using 13C-urea breath test, Helicobacter pylori IgG serology, and CagA serology. PATIENTS AND METHODS: A series of 100 dyspeptic patients were studied. Biopsies were obtained for histology and rapid urease test (gold standard). Serum samples were obtained for Helicobacter pylori IgG and CagA serology, and 13C-urea breath test was carried out. RESULTS: If endoscopy had not been performed in Helicobacter pylori patients based on 13C-urea breath test, <45 years, without alarm symptoms, and without non-steroidal anti-inflammatory drug use, 15%

Analysis of Adverse Pregnancy Outcomes of Pregnant Women with Syphilis and Maternal-Infant Serological Association in Changzhou, China, 2015-2019.

BACKGROUND: Although the prevention of mother-to-child transmission of syphilis program in China has achieved national coverage for 7 years, controversy still exists regarding the treatment of syphilis and the serological significance of syphilis. OBJECTIVE: To explore the occurrence and influencing factors of adverse pregnancy outcomes among pregnant women with syphilis in Changzhou from 2015-2019 and to further analyze the impact of syphilis serologic titers on perinatal outcomes and neonatal serologic outcomes. METHODS: Syphilis-infected pregnant women reported in Changzhou City from 2015

[The bacteriological and serological prevalence of Campylobacter spp. and Yersinia enterocolitica in fattening pig herds in Lower Saxony].

This article presents the results of a study on the occurrence of two bacteria that cause zoonoses, Campylobacter spp. and Yersinia enterocolitica. The study was carried out in 30 fattening herds in Lower Saxony, Germany, in 2004 and compares the results of bacteriological and serological methods of detection. Bacteriological findings of Campylobacter spp. in the faeces indicated that 69.7% of the fattening pigs were positive, but 81.2% tested positive serologically. All herds tested here were both bacteriologically and serologically positive for Campylobacter spp. Furthermore, only 8.4% teste

Diagnostic tests for Helicobacter pylori--can they help select patients for endoscopy?

AIM: Dyspepsia is a common symptom and some selection process for endoscopy is required. This study seeks to determine if noninvasive tests for Helicobacter pylori could be useful as a screening test to help select patients for endoscopy. METHODS: Consecutive patients attending for upper gastrointestinal endoscopy were interviewed prior to endoscopy and the endoscopic diagnoses was recorded. The presence of Helicobacter pylori infection was assessed by serology. Some patients also had a 13C urea breath test or rapid urease test (CLO test). RESULTS: 436 consecutive patients were evaluated. Th

Molecular Detection of Brucella spp. from Milk of Seronegative Cows from Some Selected Area in Bangladesh.

Brucellosis is endemic in Bangladesh both in humans and in animals. A number of reasons complicate the diagnosis, as bovine brucellosis can be diagnosed by various serological tests. But the tests have a limitation; when the organism remains intracellular, the disease goes into chronic stage and the antibody titres may decline. The present study was conducted for isolation and detection of Brucella spp. by polymerase chain reaction (PCR) from seronegative cows. A total of 360 dairy cows from three geographical regions were screened serologically by Rose Bengal Plate Test (RBPT) where 24 sample

Novel Insights into Noninvasive Assessment of Liver Fibrosis in Chronic Hepatitis C Patients.

Chronic hepatitis C (CHC) represents a significant global public health challenge, with patient prognosis intricately linked to the severity … Ts) have been developed and increasingly adopted, including abdominal ultrasound, elastography, and serologic tests. This article reviews recent advancements in noninvasive diagnostic methods for assessing liver fibrosis in CHC patients, evaluates the accuracy and reliability of these methods, and proposes individualized testing protocols tailored to patients wit …

Case Report: Positive Mycoplasma pneumoniae IgM does not necessarily indicate acute infection: two case studies.

BACKGROUND: We aimed to explore the duration of IgM antibodies against Mycoplasma pneumoniae. METHODS: Data from two children who consistently tested positive for M. pneumoniae IgM antibodies were retrospectively analyzed. Moreover, we examined the etiological data and drug use of these cases. Serologic testing using the colloidal gold method, direct chemiluminescence technique, and specific immune agglutination test were utilized. Quantitative PCR was used to detect M. pneumoniae in bronchoalveolar lavage fluid and antigen tests and nucleic acid detection were conducted for other respiratory

Synovial microenvironment and fluorescence imaging for early rheumatoid arthritis diagnosis.

Rheumatoid arthritis (RA) is a chronic, systemic autoimmune inflammatory disease that primarily affects the joints and surrounding soft tissues. Early diagnosis is crucial for preventing joint damage and improving the prognosis and quality of life in RA patients. Therefore, this article reviews conventional diagnostic methods, such as serologic tests (including rheumatoid factor (RF), anti-citrullinated protein antibody (ACPA), and anti-carbamylated protein (anti-CarP)) and imaging tests and also focuses on innovations in AI-driven diagnostic and therapeutic technologies. Additionally, we prov…

[Four-year follow-up of a neurosyphilis case presenting psychiatric symptoms].

The authors present a case of neurosyphilis associated with predominant psychiatric symptoms. The elderly man was admitted because of confus … nd pleocytosis and elevated cerebrospinal fluid protein levels. Neurosyphilis had been confirmed by serologic tests. The cognitive symptoms improved and the psychiatric symptoms remitted under penicillin treatment. Four years after diagnosis, there is a gradual progression in the cognitive decline. Two additional hospitalizations were necessary due to the relapse …