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Anterior cerebral artery embolism during thrombectomy increases disability and mortality.

OBJECTIVE: During thrombectomy, thromboembolic migration in previously unaffected territory may occur and is not systematically notified. We … n 65 patients (9.4%; 95% CI 7.2% to 11.6%). Internal carotid artery occlusion (tandem or terminal), Alberta Stroke Program Early CT Score <7, increasing number of passes, and use of stent retriever alone (compared with distal aspiration alone or combined with stent retriever) were found to be independent predictors of ACAE. Compared with patients without …

Gross Motor Trajectories During the First Year of Life for Preterm Infants With Very Low Birth Weight.

BACKGROUND: Early identification of motor dysfunction in preterm infants with very low birth weight (VLBW) is important in order to provide early intervention. OBJECTIVE: This study was to examine the motor trajectories of preterm infants with VLBW during their first year of life and to investigate the predictive ability and influencing factors of the trajectories. DESIGN AND METHODS: A total of 342 preterm infants with VLBW were prospectively assessed for motor development by the Alberta Infant Motor Scales at 4, 6, 9, and 12 months and for developmental outcomes using the Bayley Scales of …

The Influence of Native Language on Auditory-Perceptual Evaluation of Vocal Samples Completed by Brazilian and Canadian SLPs.

OBJECTIVE: This study aimed to determine the influence of native language on the auditory-perceptual assessment of voice, as completed by Brazilian and Anglo-Canadian listeners using Brazilian vocal samples and the grade, roughness, breathiness, asthenia, strain (GRBAS) scale. STUDY DESIGN: This is an analytical, observational, comparative, and transversal study conducted at the Speech Language Pathology Department of the Federal University of Minas Gerais in Brazil, and at the Communication Sciences and Disorders Department of the University of Alberta in Canada. METHODS: The GRBAS scale, c…

Связана ли ранняя смертность от туберкулеза с увеличением числа случаев передачи туберкулеза?

ВВЕДЕНИЕ: туберкулез (ТБ) в настоящее время является относительно редким заболеванием в странах с высоким уровнем дохода. Таким образом, его диагноз может быть пропущен или отложен, что приведет к смерти до или вскоре после введения лечения. Неизвестно, связана ли ранняя смерть от туберкулеза с увеличением числа случаев передачи туберкулеза. Для определения риска передачи, связанного с ранней смертью от туберкулёза, мы провели тематическое исследование. МЕТОДЫ: Все взрослые, у которых: 1) в провинции Альберта, Канада, в 1996−2012 годах был диагностирован ВИЧ-инфицированный легочный туберкулез,

Совпадение в аннотации оригинала
INTRODUCTION: Tuberculosis (TB) is now a relatively uncommon disease in high income countries. As such, its diagnosis may be missed or delay … METHODS: All adults who were: (1) diagnosed with culture-positive pulmonary TB in the Province of Alberta, Canada between 1996 and 2012, and (2) died a TB-related death before or within the first 60 days of treatment, were identified. For each of these "cases" two sets of "controls" were randomly selected from among culture-positive pulmonary TB cases t …

Complementary and alternative medicine: a survey of its use in pediatric cardiology.

BACKGROUND: The use of complementary and alternative medicine is high among children and youth with chronic illnesses, including patients wi … s) presenting to 2 hospital-based cardiology clinics: the Stollery Children's Hospital in Edmonton, Alberta, and the Children's Hospital of Eastern Ontario in Ottawa, Ontario. RESULTS: At the Stollery Children's Hospital, 64.1% of the 145 respondents had used complementary and alternative medicine compared with 35.5% of the 31 respondents at the Children …

Mobility of Vulnerable Elders study: effect of the sit-to-stand activity on mobility, function, and quality of life.

OBJECTIVES: The aim of this study is to assess the effect of the sit-to-stand activity on the mobility, function, and health-related quality … nstrument Minimum Data Set (Version 2.0), and the facility context covariate was measured using the Alberta Context Tool. RESULTS: A total of 111 residents completed the 6-month trial (56 intervention; 55 control). Residents in the intervention facilities maintained mobility, as measured by the time to complete one sit-to-stand (P = .01), and experienced …

Effects of injury severity and cognitive exaggeration on olfactory deficits in head injury compensation claims.

The purpose of this study was to examine the relationship between exaggeration and scores on a test of olfactory discrimination in patients being assessed in connection with a claim for financial benefits. Participants were 448 patients referred to a private practice in Edmonton, Alberta, Canada for psychological or neuropsychological assessment, related to evaluation of impairment and disability resulting from a work-related or non-work related accident. All patients were involved in some form of compensation claim at the time of their evaluation. All patients completed two tests designed to …

Sunlight exposure, pigmentary factors, and risk of nonmelanocytic skin cancer. I. Basal cell carcinoma.

BACKGROUND AND DESIGN: Basal cell carcinoma (BCC) of the skin is the most common neoplasm in white populations, and solar radiation is gener … , 1983, through December 31, 1984, and 406 randomly selected male control subjects was conducted in Alberta, Canada. The study was conducted using a standardized questionnaire, administered in person by trained interviewers. Data were analyzed using conditional logistic regression methods. RESULTS: After controlling for other host and pigmentary factors, …

Foodborne and Waterborne Disease in Canada - 1983 Annual Summary.

Data on foodborne disease in Canada in 1983 are compared with those for 1982. A total of 963 incidents, comprising 752 outbreaks and 211 sin … ation basis, incidents were greatest in Ontario, followed by those in Quebec, British Columbia, and Alberta. Details of several foodborne disease incidents are presented. In addition, two incidents of waterborne disease were documented in 1983, two fewer than in 1982. Giardia lamblia was the etiologic agent in one of them.

Disparities in Access to Vascular Stroke Imaging and Carotid Revascularization: A Population Study.

BACKGROUND: Decisions on imaging with computed tomography angiography, magnetic resonance angiography, and ultrasound in stroke or transient ischemic attack (TIA) may be influenced by factors ranging from location-based resource considerations to patient characteristics. We investigated disparities in vascular imaging utilization and carotid revascularization over 7 years in a Canadian province (Alberta, population: 4.4 million). METHODS: We used provincial administrative data encompassing patients presenting to hospital or emergency/urgent-care facilities with TIA or ischemic stroke from Apr…

A Longitudinal Study on the Association Between Diabetic Foot Disease and Health-Related Quality of Life in Adults With Type 2 Diabetes.

OBJECTIVES: The aim of this study was to assess the association between diabetic foot disease and health-related quality of life (HRQOL) during a 2-year follow up among people with type 2 diabetes in Alberta. METHODS: A type 2 diabetes cohort was established (2011‒2013); those with self-reported diabetic foot disease were identified. HRQOL was assessed at baseline and 1 and 2 years. Scores from the 12-item Short Form Physical Component Summary (PCS) and Mental Component Summary (MCS) and the EuroQol 5-Dimension 5-Level (EQ-5D-5L) instrument were collected. The association between diabetic foo…

Prevalence of sarcopenic obesity in adults with end-stage knee osteoarthritis.

OBJECTIVE: To identify the prevalence of sarcopenic obesity, a phenotype of low muscle mass and high adiposity, in adults with end-stage knee osteoarthritis (OA). Various diagnostic criteria, including assessment of muscle/fat mass, muscle strength and physical function, were used to identify patients with and without sarcopenic obesity, and to compare outcomes of pain, function and quality of life. DESIGN: Cross-sectional clinical study including adults with a body mass index (BMI) ≥30 kg/m2 and knee OA. Body composition was measured by dual-energy X-ray absorptiometry (DXA). Assessments inc

Contributions of environment, comorbidity, and stage of dementia to the onset of walking and eating disability in long-term care residents.

OBJECTIVES: To estimate the relative effects of environment, comorbidities, stage of dementia and other variables on disability onset. DESIGN: A 1-year prospective cohort study was conducted in which the walking and eating abilities of long-term care residents were observed fortnightly. Structural equation modeling was used to assess the contributions of individual and environmental factors to the onset of disability. SETTING: Fifteen nursing homes in western Canada. PARTICIPANTS: One hundred twenty residents with middle-stage Alzheimer disease or related dementia. MEASUREMENTS: Environmen

The changing face of childhood celiac disease in north america: impact of serological testing.

OBJECTIVE: The goal was to evaluate the impact of immunoglobulin A endomysial antibody testing on the incidence and clinical presentation of childhood celiac disease. METHODS: The incidence and clinical presentation of celiac disease in patients <18 years of age in 1990-1996 (pretesting group) versus 2000-2006 (testing group) were compared. RESULTS: The median age at diagnosis was 2 years (95% confidence interval: 2-4 years) in the pretesting group (N = 36), compared with 9 years (95% confidence interval: 8-10 years) in the testing group (N = 199; P < .001); the female/male ratios (1.6:1) we

Air pollution and daily ED visits for migraine and headache in Edmonton, Canada.

BACKGROUND: A variety of environmental factors have been identified as possible triggers for migraine and other headache syndromes. OBJECTIVE: We analyzed associations between air pollution and emergency department (ED) visits for migraine and headache. METHODS: Analysis was based on 56,241 ED visits for migraine and 48,022 ED visits for headache to Edmonton hospitals between 1992 and 2002. A Poisson model of counts hierarchically clustered by day of week, month, and year was applied using generalized linear mixed models. Temperature and relative humidity were included as covariates. RESULT

QT intervals in metabolic dilated cardiomyopathy.

OBJECTIVES: The present study determined the prevalence of dilated cardiomyopathy together with prolonged corrected QT (QTc) intervals in children. The study also examined whether an association exists between prolonged QTc intervals and ventricular dysrhythmia in a patient cohort with dilated cardiomyopathy. BACKGROUND: The morbidity and mortality for pediatric patients with dilated cardiomyopathy remains high and is a clinical challenge. The patient population includes a significant number of Hutterite patients with metabolic disease associated with dilated cardiomyopathy. METHODS: Thirty-

Absence of linkage of phonological coding dyslexia to chromosome 6p23-p21.3 in a large family data set.

Previous studies have suggested that a locus predisposing to specific reading disability (dyslexia) resides on chromosome 6p23-p21.3. We investigated 79 families having at least two siblings affected with phonological coding dyslexia, the most common form of reading disability (617 people genotyped, 294 affected), and we tested for linkage with the genetic markers reported to be linked to dyslexia in those studies. No evidence for linkage was found by LOD score analysis or affected-sib-pair methods. However, using the affected-pedigree-member (APM) method, we detected significant evidence for

Central venous catheters as a source of hemodialysis-related bacteremia.

OBJECTIVE: To describe investigations into an increase in hemodialysis-related bacteremia that occurred in our hospital in the first 6 months of 1996. SETTING: Hemodialysis unit in a tertiary-care medical center. METHODS: Prospective surveillance for hemodialysis bacteremia has been performed for several years. Cases that occurred in 1995 were compared to cases in the first 6 months of 1996. Unit data on dialysis runs and method of dialysis access were used to calculate rates. Nested polymerase chain reaction (PCR) was used to type 18 Staphylococcus aureus isolates from 1996. A case-control

Five-Day Glycemic Patterns and 3-Month Functional Outcomes After Endovascular Thrombectomy.

BACKGROUND AND PURPOSE: Admission hyperglycemia is associated with poor outcomes after endovascular thrombectomy (EVT) for acute ischemic st … 63 (19.7%) in Group 3. Groups 2 and 3 had more diabetes and higher hemoglobin A1c; stroke severity, Alberta Stroke Program Early Computed Tomography Scores, and reperfusion status were comparable. Both hyperglycemic groups had lower odds of a favorable mRS shift than Group 1 (adjusted common odds ratio [OR] 0.35, 95% confidence interval [CI] 0.20-0.61 and …

Structural and metabolic imaging after mechanical thrombectomy for acute ischemic stroke: A hybrid 18F-FDG PET/MRI pilot study.

Hybrid 2-[18F]-fluoro-2-deoxy-D-glucose positron emission tomography/magnetic resonance imaging (18F-FDG PET/MRI) enables simultaneous, single-session assessment of structural and metabolic stroke damage. We prospectively studied 10 consecutive patients (6 women; mean age 71.6 ± 11.2 years) with anterior-circulation stroke due to middle cerebral artery (MCA) occlusion who underwent successful mechanical thrombectomy (MT). Structural damage was graded with the Alberta Stroke Program Early CT Score (ASPECTS) on admission and 24-h non-contrast CT and on diffusion-weighted imaging (DWI) and fluid-…