Результаты поиска

Revision of total hip arthroplasty by long locking stem with fully hydroxyapatite-coated modular metaphysis (Reef™): A continuous series of 78 cases at a minimum 2-year follow-up.

INTRODUCTION: Since the Wagner and Vives stems were introduced in the 1980s, the range of uncemented implants for femoral revision has grown … adiographic assessment used immediate postoperative views and last follow-up radiographs, assessing osseointegration, filling index and stress shielding. Implant survival was estimated following Kaplan-Meier with 95% confidence intervals. RESULTS: Mean follow-up was 6±3 years (range, 2-12). Last follow-up included 78 cases for analysis (12 deaths [13%] and 3 pati …

Optimising bionic pore designs in a spiral blade implant to enhance bone ingrowth and stability: A combined CFD and large-animal study.

PURPOSE: This study aimed to evaluate the effects of different Bionic Pore geometries (circular, triangular, and rectangular) and diameters … ons and promote bone ingrowth. Small-diameter circular holes, in particular, favor early and robust osseointegration. Moreover, this work underscores the potential of combining advanced manufacturing techniques with mechanobiological principles to design customized bionic implants for enhanced orthopedic outcomes. Importantly, the close agreement between CFD predi …

A Comparative Evaluation of Advanced Platelet-Rich Fibrin and Titanium Platelet-Rich Fibrin in Maxillary Sinus Augmentation Using the Crestal Approach.

Aim and objectives The present clinical investigation aimed to evaluate and compare the influence of advanced platelet-rich fibrin (A-PRF) a … f growth factors associated with T-PRF may have contributed to its superior performance in terms of osseointegration and bone maturation. Conclusions The results of this study support the use of T-PRF as a more effective adjunct in sinus augmentation procedures via the crestal approach. When used in combination with a bovine xenograft, T-PRF leads to improved impl …

Changes in stability and marginal bone level around implants with hydrophilic and hydrophobic surfaces for posterior tooth replacement: A 1-year randomized clinical trial.

AIM: This two-group parallel, double-blind, randomized clinical trial compared the 1-year changes in longitudinal stability and marginal bone level (MBL) between implants with hydrophilic (HPL) and hydrophobic (HPB) surfaces. MATERIALS AND METHODS: Patients with single posterior edentulous spaces were randomly assigned to two groups (HPL and HPB), and implants were inserted using a guided protocol. Screw-retained provisional and metal-ceramic crowns were provided per the manufacturer's loading protocol. The implant stability quotient (ISQ) was measured immediately and after 15, 30, 45 (HPL lo

The osteogenesis performance of titanium modified via plasma-enhanced chemical vapor deposition: in vitro and in vivo studies.

Titanium (Ti) and its alloys are widely used in dental implants due to their favorable mechanical properties and biocompatibility. Surface characteristics, including physical and chemical properties, are crucial factors to enhance the osteogenesis performance of Ti. The aim of this study is to evaluate amino group surface modification to facilitate the osteogenic potential and bone repair of dental implants both in vitro and in vivo. Herein, amino group-modified Ti surfaces were constructed via the plasma-enhanced chemical vapor deposition (PECVD) technique with an allylamine monomer. The adhe

Carbon/PEEK nails: a case-control study of 22 cases.

BACKGROUND: Interest around carbon/PEEK plates and nails has been raising. The elastic modulus close to the bone, the high load-carrying capacity and radiolucency make CFR/PEEK materials a potential breakthrough. In the literature, there are abundant data about CFR/PEEK plates in the treatment of proximal humerus, distal radius and distal fibula fractures. In patients affected by bone metastasis, CFR/PEEK nails were proved effective and safe with 12 months of follow-up. Very little is known about performances of CFR/PEEK nails in patients affected by other pathologies. PURPOSES: The aim of th

The effects of bone pâté on human osteoblasts cell cultures.

The aim of the present study was to evaluate the effect of bone pate on human osteoblast differentiation by measuring cell viability, alkaline phosphatase activity and expression of the transcription factors and of the major components of the extracellular matrix. Although bone paté has been used in ear surgery for many years and when placed in contact with mastoid and external auditory canal bone become viable, the cellular mechanisms that lead to its osteointegration have never been described. Bone paté taken from four patients subjected to mastoidectomy and affected by middle ear and mastoi

The role of stability measurements of the Baha® system in children.

OBJECTIVE: Percutaneous bone conduction hearing aids are an established treatment for selected children unable to use conventional hearing aids. Currently in children, loading the implant is delayed for 3-6 months following fixture placement, due to concerns regarding bone quality, bone thickness and subsequent implant stability. Traditionally, such concerns led to children undergoing 2-stage Baha(®) surgery, with a second operation to attach the abutment after 3-6 months. Bone conduction implant stability can be objectively measured using resonance-frequency analysis (RFA) to generate Implant

Biological advantages of porous hydroxyapatite scaffold made by solid freeform fabrication for bone tissue regeneration.

Presently, commercially available porous bone substitutes are manufactured by the sacrificial template method, direct foaming method, and polymer replication method (PRM). However, current manufacturing methods provide only the simplest form of the bone scaffold and cannot easily control pore size. Recent developments in medical imaging technology, computer-aided design, and solid freeform fabrication (SFF), have made it possible to accurately produce porous synthetic bone scaffolds to fit the defected bone shape. Porous scaffolds were fabricated by SFF and PRM for a comparison of physical and

Clinical and radiographic evaluation of total hip arthroplasties using porous tantalum modular acetabular components: 5-year follow-up of clinical trial.

OBJECTIVES: Porous tantalum is a biomaterial newly applied for artificial joints. We present here 5-years follow-up report of a multicenter clinical trial of total hip arthroplasties (THA) with porous tantalum modular acetabular component (modular PTC). METHODS: Study participants received 82 hips in 79 cases, with 61.2 months follow-up on average. Age at operation was 60.9 years. Clinical results were evaluated using Merle d'Aubigne Postel score. Presence of implant loosening, periacetabular radiolucency, osteolysis, and gap filling were examined for radiographic results. RESULTS: Merle d'A

Bone regeneration using porous titanium particles versus bovine hydroxyapatite: a sinus lift study in rabbits.

AIM: The first objective of this study was to qualitatively and quantitatively assess the bone formation process, particularly the long-term behavior and three-dimensional volume stability of subsinusal bone regeneration, using titanium (Ti) or bovine hydroxyapatite (BHA) granules, in a rabbit model. The second objective was to evaluate the effect of the hydration of the BHA particles with a therapeutic concentration of doxycycline solution on the osteogenesis and biomaterial resorption. MATERIALS AND METHODS: Rabbits underwent a double sinus lift procedure using one of three materials: grade

Osteochondral mosaicplasty of the femoral head.

Young adults with osteochondral lesions of the femoral head are at risk of rapid progression to symptomatic arthritis of the hip joint. Between January 2008 and July 2009, 10 patients were treated for femoral cartilage damage by a osteochondral mosaicplasty of the femoral head through a trochanteric flap with dislocation of the hip. The consecutive series had the following exclusion criteria: acetabular chondropathy, age above 25 years, and femoral head osteonecrosis. Patients were followed up after surgery using the Oxford-12 score, Harris hip score and the Merle d'Aubigné score, and activity

A 5-year prospective clinical study of submerged and nonsubmerged Paragon system implants in the edentulous mandible.

PURPOSE: The aim of this investigation was to evaluate the clinical outcome of two different surgical protocols in the edentulous mandible: submerged and nonsubmerged. Further, the Paragon dental implant with a titanium plasma-sprayed surface was evaluated. MATERIALS AND METHODS: Twenty-nine consecutively treated patients with 168 implants supporting fixed prostheses were included. All but 3 patients were provided 6 implants, placed via nonsubmerged healing on one side and submerged healing on the other. Data were collected from patient records and radiographs. Twenty-four patients participat

Lower dose of rhBMP-2 achieves spine fusion when combined with an osteoconductive bulking agent in non-human primates.

STUDY DESIGN: A non-human primate lumbar intertransverse process arthrodesis model was used to evaluate the effectiveness of different formulations of recombinant human bone morphogenetic protein-2 (rhBMP-2) to induce consistent bone formation. OBJECTIVE: To determine if the combination of rhBMP-2/absorbable collagen sponge (ACS) wrapped around a bulking agent, consisting of a biphasic calcium phosphate/collagen composite, could achieve posterolateral spine fusion with a dose of rhBMP-2 (3.0 mg/side) that previously failed to induce posterolateral fusion in rhesus monkeys with other carriers.

Satisfactory results of Stanmore total hip arthroplasty after failed osteosynthesis of the femoral neck.

Treatment of fractures of the femoral neck by closed reduction and internal fixation results in a high incidence of complications, and often requires secondary total hip arthroplasty. We retrospectively studied 31 patients who underwent a Stanmore (Howmedica) total hip arthroplasty performed five months (median) after osteosynthesis. The most common indications were: failure of fixation (n = 14), osteonecrosis (n = 9) and secondary osteoarthritis (n = 6). Eight patients had a maximum follow-up of 12 months; the median follow-up was 30 months in the remaining group of 23 patients. Although one

Brånemark implants and osteoporosis: a clinical exploratory study.

BACKGROUND: Oral implant treatment on patients with poor jaw-bone texture has shown increased failure rates in series of studies. PURPOSE: The purpose of the present study was to retrospectively follow patients with osteoporosis of the axial or appendicular skeleton, including the jaw bone, being subjected to oral implant treatment. The outcome of inserted implants, when using an adapted bone site preparation technique and extended healing periods, was evaluated. MATERIALS AND METHODS: Based on data obtained from preoperative radiographs, patient medical history, and resistance of the jaw bo

Endosteal implants in the irradiated lower jaw.

Since 1990 Endosteal implants have been inserted in the irradiated lower jaw at our clinic. IMZ implants have been used for dental rehabilitation in 26 patients (21 male, 5 female) suffering from squamous cell carcinomas stage T2-T4 136. The implants were either placed in local bone and soft tissue (group 1, n = 60 implants), or in local bone after marginal mandibulectomy and transplanted soft tissue (group 2, n = 26 implants), or in transplanted bone and soft tissue (group 3, n = 52 implants). Life-table analysis according to Kaplan-Meier demonstrated a 3-year implant survival rate of 87.8% i

Dental implants in immunocompromised patients: a systematic review and meta-analysis.

ObjectiveImpaired health conditions and related lack of adequate host healing are among the most important conditions that account for dental implant failure. Today clinicians face an increasing number of immunocompromised patients requesting implant-based rehabilitation. To provide clinical evidence for prospective decision-making, the aim of this systematic review and meta-analysis was to analyse the influence of immunodeficiency on dental implant survival.MethodsThe study was conducted according to the PRISMA Statement and the principles of the Cochrane Collaboration. MEDLINE and Web of Sci

Совпадение в полном тексте источника
… Besides post-operative wound healing, the osseointegration of the inserted implant is one of the foremost steps towards successful rehabilitation [ 7 ]. … Only one out of four implants was lost in one case after 4 months due to failed osseointegration, but could be replaced successfully [ 38 ]. The detected causes of implant failure were peri-implantitis, tilted implants, failed osseointegration, and early infection. …

A Prospective Assessment of Periprosthetic Bone Mineral Density and Osteoimmunological Biomarkers Variations After Total Knee Replacement Surgery.

Aseptic loosening is a major cause of premature failure of total knee replacement (TKR). Variations in periprosthetic bone mineral density (BMD) and osteoimmunological biomarkers levels could help to quantify prosthesis osteointegration and predict early aseptic loosening. The gene expression of 5 selected osteoimmunological biomarkers was evaluated in tibial plateau bone biopsies by real-time polymerase chain reaction and changes in their serum levels after TKR were prospectively evaluated with enzyme-linked immunosorbent assay for 1 yr after surgery. These variations were correlated to chang

Multiscale analyses of the bone-implant interface.

Implants placed with high insertion torque (IT) typically exhibit primary stability, which enables early loading. Whether high IT has a negative impact on peri-implant bone health, however, remains to be determined. The purpose of this study was to ascertain how peri-implant bone responds to strains and stresses created when implants are placed with low and high IT. Titanium micro-implants were inserted into murine femurs with low and high IT using torque values that were scaled to approximate those used to place clinically sized implants. Torque created in peri-implant tissues a distribution