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Occlusio Pupillae: A Duet of Darkness Where the Patient Sees Naught, and the Doctor Discerns Not.

A 71-year-old, one-eyed female patient presented with a loss of vision in the right eye due to trauma 20 years ago and a progressive diminut … lization of the uveitis over the next few weeks and under a steroid cover, a temporal clear-corneal phacoemulsification was cautiously performed with intra-operative management of the small pupil, and a hydrophobic lens was implanted. At one month post-surgery, the patient's best-corrected visual acuity had improved to 6/12 for distance and N6 for near. This report h …

Role of preoperative anterior segment optical coherence tomography in identifying intraoperative posterior capsular dehiscence in posterior polar cataract.

INTRODUCTION: The presence of preoperative posterior capsular dehiscence in posterior polar cataracts (PPCs) increases the chances of intraoperative posterior capsular rent. Our study aims to demonstrate the efficacy of preoperative anterior segment optical coherence tomography (ASOCT) to predict intraoperative posterior capsular rupture (PCR) in PPC. MATERIALS AND METHODS: This was an observational study including patients within 25-75 years of age, having PPC, undergoing phacoemulsification. ASOCT was done for evaluating preoperative posterior capsular status and was graded as "intact" or "…

Dexamethasone Intracameral Drug-Delivery Suspension for Inflammation Associated with Cataract Surgery: A Randomized, Placebo-Controlled, Phase III Trial.

PURPOSE: To evaluate the safety and efficacy of an anterior chamber intracameral dexamethasone drug-delivery suspension (IBI-10090; DEXYCU; Icon Bioscience Inc., Newark, CA) that provides medication for up to 21 days with a single application in treating postoperative inflammation in patients undergoing cataract surgery. DESIGN: Prospective, randomized, double-masked, multicenter trial. PARTICIPANTS: Patients with preoperative best-corrected visual acuity of 20/30 to 20/200 undergoing unilateral cataract surgery by phacoemulsification were randomized to receive IBI-10090 or placebo. METHODS…

Clinical Outcomes of Preloaded Descemet Membrane Endothelial Keratoplasty Grafts With Endothelium Tri-Folded Inwards.

PURPOSE: To evaluate the initial outcomes and complications of Descemet membrane endothelial keratoplasty (DMEK) using donor tissues tri-fol … the surgeon. Standardized DMEK was performed as a single procedure (n = 15) or in combination with phacoemulsification and IOL implantation (n = 31) within 48 hours from preparation using a bimanual pull-through technique. MAIN OUTCOME MEASURES: Preparation and surgical times, intraoperative and postoperative complications, best spectacle-corrected visual acuity (B …

Perioperative modulating factors on astigmatism in sutured cataract surgery.

PURPOSE: To evaluate the factors that affect postoperative astigmatism and post-suture removal astigmatism, and to evaluate the risk factors associated with astigmatism axis shift. METHODS: We performed a retrospective chart review of 130 eyes that had undergone uneventful phacoemulsification cataract surgery. Preoperative astigmatism was divided into four groups (Groups I, II, III, and IV) according to the differences between the axis of preoperative astigmatism (flattest axis) and the incision axis (105 degrees). We analyzed the magnitude and axis of the induced astigmatism after the operat…

Multidisciplinary Management of Morbidities Associated with Chronic Graft-Versus-Host Disease.

Chronic graft-versus-host disease (cGVHD) represents a common long-term complication after allogeneic hematopoietic stem cell transplantation (HSCT). It imposes a significant morbidity burden and is the leading cause of non-relapse mortality among long-term HSCT survivors. cGVHD can manifest in nearly any organ, severely affecting the quality of life of a transplant survivor. While the mainstay of treatment has remained systemic immunosuppression with glucocorticoids, progress has been made within the last few years with approvals of three oral agents to treat steroid-refractory cGVHD: ibrutin

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… sensation Conjunctivitis, conjunctival fibrosis Corneal ulceration or perforation Glaucoma Cataracts | Ophthalmologic evaluation: slit lamp exam, corneal fluorescein staining, Schirmer’s test, tonometry | Ophthalmology referral Artificial tears Topical steroids and calcineurin inhibitors Scleral lenses Phacoemulsification … Outcomes of phacoemulsification in patients with chronic ocular graft-versus-host disease. Saboo U. S., Amparo F., Shikari H., Jurkunas U. V., Dana R. 2015Graefes Arch Clin Exp Ophthalmol. 253(6):901–907. doi: 10.1007/s00417-015-2940-3. doi: 10.1007/s00417-015-2940-3. …

Impact of pupil size on defocus curve, contrast sensitivity, and patient satisfaction in a diffractive, simultaneous vision intraocular lens.

PURPOSE: To evaluate the relationship between pupil size (PS) and defocus curve, contrast sensitivity (CS), spectacle independence, and patient satisfaction after implantation of a diffractive, simultaneous vision intraocular lens (SVL; AcrySof IQ PanOptix). SETTING: Department of Ophthalmology, Goethe-University, Frankfurt, Germany. DESIGN: Post hoc analysis of prospective studies. METHODS: Patients were included 3 months after bilateral implantation of a diffractive SVL. Exclusion criteria included any ocular pathologies or previous ocular surgeries besides cataract or refractive lens exc

Refractive outcomes after secondary scleral-sutured toric intraocular lenses for the correction of corneal astigmatism.

PURPOSE: To describe refractive outcomes in eyes with regular corneal astigmatism undergoing scleral-sutured toric intraocular lens (SS-TIOL) placement with complete pars plana vitrectomy using an MX60 toric intraocular lens (IOL) and 8-0 Gore-Tex suture. SETTING: Academic clinical hospital, Mayo Clinic, Rochester, Minnesota. DESIGN: Retrospective, single-institution, consecutive case series. METHODS: All eyes in patients with more than 1.0 diopter (D) of regular astigmatism undergoing secondary IOL implantation were included. Patients with irregular astigmatism or aged younger than 18 year

Comparison of flanged intrascleral haptic fixation and 2-point transscleral Gore-Tex-sutured IOL fixation: 12-monthcohort study.

PURPOSE: To compare the short-term and long-term visual and refractive outcomes between flanged intrascleral haptic fixation (FIHF) and 2-point transscleral polymethyl methacrylate (PMMA) intraocular lens (IOL) fixation using Gore-Tex sutures in patients lacking capsular support. SETTING: National Cheng Kung University Hospital, Tainan, Taiwan. DESIGN: Retrospective cohort study using propensity score matching to minimize baseline differences between groups. METHODS: Medical records of adult patients who underwent FIHF or Gore-Tex-sutured IOL fixation between 2014 and 2024 were reviewed. Pa

MICROSCOPE-INTEGRATED INTRAOPERATIVE OPTICAL COHERENCE TOMOGRAPHY FOR INTRAOCULAR LENS TILT EVALUATION DURING SCLERAL-SUTURE FIXATION.

PURPOSE: The aim of this study was to evaluate the feasibility and clinical utility of a commercially available microscope-integrated intraoperative optical coherence tomography (MI-OCT) system during scleral-sutured fixation of intraocular lenses (IOLs). METHODS: Scleral-sutured IOL fixation was performed in 18 eyes using the Zeiss Rescan 700 MI-OCT system. Intraoperative optical coherence tomography images were captured, and the utility of MI-OCT in the procedure was assessed. RESULTS: Eighteen eyes from 18 patients underwent scleral-sutured IOL fixation using the MI-OCT system. The system

Biometry-Guided IOL Formula Selection in Post-Laser Vision Correction Eyes.

PURPOSE: To determine whether objective biometry can guide intraocular lens formula selection in post-laser vision correction (LVC) eyes with indeterminate classification of actual LVC type (total keratometry [TK] TKave - keratometry [K] Kave = 0.00 to 0.06), and to compare refractive accuracy among contemporary LVC formula strategies. METHODS: A total of 507 post-LVC eyes (inclusive of both myopic [M-LVC] and hyperopic [H-LVC] eyes) with TKave - Kave between 0.00 and 0.06 measured by swept-source optical coherence tomography biometry (IOLMaster 700; Carl Zeiss Meditec AG) were analyzed. Refr

Preliminary clinical observation of unilateral implantation of trifocal intraocular lens.

BACKGROUND: Evidence on unilateral trifocal IOL implantation is limited. This study evaluates the clinical outcomes of unilateral implantation of the AcrySof IQ PanOptix TFNT00 trifocal intraocular lens (IOL) in cataract patients. METHODS: This study included 55 eyes of 55 cataract patients who underwent unilateral TFNT00 trifocal IOL implantation. Comprehensive evaluations were performed preoperatively and postoperatively at 1, 3, 6, and 12 months. Outcome measures included uncorrected distance visual acuity (UDVA), uncorrected intermediate visual acuity (UIVA), uncorrected near visual acuit

Refractive tolerance in the use of monofocal intraocular lenses enhanced with new aspheric design.

PURPOSE: To evaluate the refractive tolerance in eyes with enhanced monocular intraocular lens (IOL) with a new aspheric design. METHODS: This study included two assessments. Clinical records of consecutive eyes with conventional monofocal IOL (SY60WF, Alcon) were retrospectively reviewed, and changes in uncorrected distance visual acuity (UDVA) with myopic and hyperopic refractive errors were evaluated using segmented regression analysis. Next, in 39 eyes of 39 cataract patients who received an enhanced monofocal IOL (NSP-3, Nidek), UDVA, refractive error, and photopic and mesopic contrast s

Two novel extended depth-of-focus intraocular lenses targeted for mini-monovision: A prospective randomized controlled trial.

PURPOSE: To compare the visual outcomes of two extended depth-of-focus (EDOF) intraocular lenses (IOLs). DESIGN: Single-center prospective randomized controlled trial. METHODS: Patients undergoing bilateral cataract surgery were randomly assigned to receive either the Acunex Vario IOL (Teleon Surgical B.V., Spankeren, The Netherlands) or the AcrySof IQ Vivity IOL (Alcon Laboratories Inc., Fort Worth, United States of America); both Vario-group and Vivity-group were targeted for mini-monovision. The primary outcome was the uncorrected intermediate visual acuity (UIVA, measured at 66cm). Secon

Comparison of intraocular lens formula accuracy for eyes with prior scleral buckle surgery.

PURPOSE: To compare intraocular lens (IOL) formula prediction accuracy for patients with previous scleral buckling surgery. SETTING: Single academic center in Los Angeles, California. DESIGN: Retrospective study. METHODS: Patients who had cataract extraction after scleral buckle surgery from 2014 to 2024 were included. The spherical equivalent prediction error (SEQ-PE) from Barrett Universal II (BUII), Hoffer QST, Holladay 1, Kane, Radial Basis Function (RBF) 3.0, and SRK/T was evaluated. The Wang-Koch-adjusted axial lengths were used for eyes >25.0 mm for the Holladay 1 and SRK/T formulas.

Optical and clinical outcomes of a new diffractive trifocal intraocular lens.

PurposeTo optically characterize and clinically evaluate the new trifocal AT ELANA 841P intraocular lens (IOL).MethodsThe optical imaging performance was assessed using an on-bench model eye through the Through-Focus Modulation Transfer Function Area (TF-MTFa) from +1.00 to -3.50D. The clinical study included manifest refraction, uncorrected (UDVA) and corrected (CDVA) distance visual acuities, distance-corrected intermediate (DCIVA) and near visual acuity (DCNVA), binocular photopic and mesopic contrast sensitivity (CS) and binocular defocus curve. Postoperative evaluation was performed 3 mon

Comparison of microperimetry outcomes in monofocal and trifocal intraocular lens recipients.

PURPOSE: This study aimed to compare the effects of trifocal (TF) and monofocal intraocular lenses (Mono-IOL) on microperimetry outcomes in patients who underwent uncomplicated cataract surgery. METHODS: A total of 44 Mono-IOL and 38 TF-IOL recipients were evaluated six months postoperatively. Corrected distance visual acuity (CDVA) was assessed using a standard logMAR chart. Microperimetry assessments were performed using the MP-1 microperimeter to measure retinal sensitivity (RS) at 2°, 6°, and 10°, fixation points (FP) within 2° and 4°; and fixation stability. Fixation stability was quanti

Comparative Accuracy Of Five Modern Toric Intraocular Lens Formulas.

PURPOSE: To compare the clinical accuracy of 5 modern toric intraocular lens (IOL) calculation formulas-Barrett, EVO, Naeser/Savini combined with Hoffer QST, Kane, and Abulafia-Koch combined with Hill RBF-in predicting postoperative refractive outcomes in cataract patients with astigmatism. DESIGN: Retrospective, comparative analysis of IOL formula accuracy. SUBJECTS: One hundred forty-six eyes from 146 cataract patients with toric IOL implantation. METHODS: Biometric measurements were obtained using the Lenstar LS900, with personalized surgically induced astigmatism values applied for each

Comparative evaluation of clinical results and patient-reported outcomes of enhanced monofocal and conventional monofocal intraocular lenses.

PURPOSE: To evaluate and compare visual performance of 2 enhanced monofocal intraocular lenses (IOLs), XY1-EM (Vivinex Impress) and DIB00V (TECNIS Eyhance), with that of a conventional monofocal IOL, XY-1 (Vivinex). SETTING: Kamiamakusa General Hospital, Kumamoto, Japan. METHODS: A retrospective analysis was conducted on 130 eyes from 75 patients, including 46 eyes (27 patients) implanted with XY1-EM, 47 eyes (26 patients) with DIB00V, and 37 eyes (22 patients) with XY-1. RESULTS: Corrected distance visual acuity (CDVA) was comparable across all 3 groups. Both enhanced monofocal IOLs (XY1-E

EFFECT OF ANTERIOR CHAMBER AIR INJECTION ON INTRAOCULAR LENS STABILITY AFTER PHACOVITRECTOMY WITH GAS/AIR TAMPONADE.

PURPOSE: Anterior chamber air injection (ACAI) is a surgical technique used to decrease the occurrence of postoperative intraocular lens (IOL) haptic dislocation after phacovitrectomy with gas/air tamponade. The impact of this technique on IOL stability remains uncertain, prompting the design of this study to investigate further. METHODS: This study included 51 eyes of 51 patients who underwent phacovitrectomy with gas/air tamponade. The patients were divided into two groups: Group 1 (ACAI group, 26 eyes) and Group 2 (non-ACAI group, 25 eyes). Intraocular lens position is used to determine th