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The Impact of Childhood Sexual Abuse on Women's Sexual Health: A Comprehensive Review.

INTRODUCTION: Childhood sexual abuse (CSA) has been identified as a potent risk factor for sexual dysfunction. Certain characteristics of th … h CSA histories. Treatment research has indicated that mindfulness-based sex therapy and expressive writing treatments are particularly effective for this group. Further research is needed to clarify the mechanisms that lead to sexual dysfunction for women with abuse histories to provide more targeted treatments for sexual dysfunction among women with abu …

Investigating the relationship between fetal growth and academic attainment: secondary analysis of the Born in Bradford (BiB) cohort.

BACKGROUND: The relationship between ultrasongraphically derived estimates of fetal growth and educational attainment in the postnatal perio … o model EFW and HC. Random effects from these were related to Key Stage 1 (KS1) results in reading, writing, mathematics, science and a composite of all four (age 6-7 years), using ordinal logistic and logistic regression. Associations were adjusted for potential confounders, facilitated by directed acyclic graphs. Missing covariate data were imputed usin …

Hyperamylasemia may indicate the presence of ovarian carcinoma: A case report.

RATIONALE: Reports of malignant ovarian tumor with hyperamylasemia are very rare. We present a patient with hyperamylasemia who was diagnose … herapy regimen containing gemcitabine and capecitabine, and remained on this regimen at the time of writing. LESSONS: Ovarian carcinoma should be considered as a possibility in patients with hyperamylasemia after ruling out other potential common causes. The final diagnosis depends mainly on the clinical manifestation, laboratory results, and CT examinat …

Atazanavir and Cardiovascular Risk Among Human Immunodeficiency Virus-Infected Patients: A Systematic Review.

INTRODUCTION: Patients with human immunodeficiency virus (HIV) infection have an increased risk of cardiovascular disease (CVD). While viral … l function was not affected. FUNDING: Bristol-Myers Squibb (article processing charges and medical writing support).

Applied statistical training to strengthen analysis and health research capacity in Rwanda.

BACKGROUND: To guide efficient investment of limited health resources in sub-Saharan Africa, local researchers need to be involved in, and g … ticians and research leaders were provided ongoing in-country mentoring for analysis and manuscript writing. RESULTS: Participants reported a high level of skill, knowledge and collaborator development from class-based trainings and out-of-class mentorship that were sustained 1 year later. Five of six manuscripts were authored by multi-institution teams …

Fentanyl Iontophoretic Transdermal System (IONSYS(®)) can be Safely used in the Hospital Environment with X-Rays, Computerized Tomography and Radiofrequency Identification Devices.

INTRODUCTION: Fentanyl iontophoretic transdermal system (fentanyl ITS, IONSYS(®)) is a patient-controlled analgesia system used for the mana … and CT scans and can also be utilized in close proximity to RFID devices. FUNDING: The studies and writing of this manuscript were supported financially by The Medicines Company.

Reading in dyslexia across literacy development: A longitudinal study of effective connectivity.

Dyslexia is a literacy disorder affecting the efficient acquisition of reading and writing skills. The disorder is neurobiological in origin. Due to its developmental nature, longitudinal studies of dyslexia are of essence. They are, however, relatively scarce. The present study took a longitudinal approach to cortical connectivity of brain imaging data in reading tasks in children with dyslexia and children with typical reading development. The participants were followed with repeated measurements through Pre-literacy (6 years old), Emergent Literacy (8 years old) and Literacy (12 years old) …

Pituitary metastases: current practice in Japan.

OBJECT: With advancement of cancer treatment and development of neuroimaging techniques, contemporary clinical pictures of pituitary metasta … east cancer and renal cell cancer than in those with lung cancer. CONCLUSIONS: At the time of this writing, approximately 60% (120/201) of PMs had been treated by stereotactic radiation therapy in Japan. The median survival time was much longer than that reported in past series. To confirm the changes of clinical features and medical practice, a prospect …

Origin and Pawn scaling for adults who do and do not stutter: A preliminary comparison.

PURPOSE: In order to determine whether adults who stutter (AWS) would show changes in locus of causality during stuttering treatment and app … provided by the American Institute for Stuttering (AIS). Along with measures of treatment outcome, writing samples were analyzed for Origin and Pawn statements that indicated the participant's locus of causality. RESULTS: At the outset of treatment the AWS showed significantly greater Pawn scores than the control group of AWNS and similar occurrences of …

Моделирование и анализ врожденной иммунной реакции, вызванной носителями вируса гепатита С.

Углубленное понимание сложных систем, таких, как инфицирование вирусом гепатита С (ГХВ) и реакция на иммунодуляторы, является открытой задачей для биологов. Для того чтобы понять механизмы, связанные с уклонением от иммунитета с помощью ВКВ, мы представляем упрощенную формализацию высокодинамичной системы, состоящей из ВКВ, цикла ее копирования и иммунной реакции на клеточном уровне с использованием гибридной сети Петри (HPN). Подход, использованный в этом исследовании, включает в себя поэтапное моделирование, проверку моделей и анализ иммунной реакции принимающей страны. Это исследование было

Совпадение в аннотации оригинала
An in-depth understanding of complex systems such as hepatitis C virus (HCV) infection and host immunomodulatory response is an open challen … targeted manipulation in the presence of HCV. The results are in complete agreement at the time of writing with the published expression studies and western blot experiments. Our model also provides some biological insights regarding the role of PKR in the acute infection of HCV. It might help to explain why many patients fail to clear acute HCV infectio …

Leiomyomatosis peritonealis disseminata associated with endometriosis: A case report and review of the literature.

Leiomyomatosis peritonealis disseminata (LPD) is a specific type of leiomyomatosis with an unclear pathogenesis that is rarely diagnosed by … n October 2014, a gynecological sonography examination revealed no abnormalities and at the time of writing, the patient remains alive and well.

Association between audiological profile and primary language impairment in children.

OBJECTIVES: The aim of the present study was to characterize the Brazilian Portuguese speaking children seen at the Speech-Language Pathology Service of a Health Center, between 1985 and 2009, diagnosed with primary language impairments (PLI): language development impairment (LDI), phonological disorder (PD) and reading and writing impairment (RWI) regarding demographic and audiological profile; as well as investigate the association between PLI and demographic variables, and the association between PLI and hearing disorders. METHODS: A survey of medical records was carried out, collecting au…

Design of the Revascularization With Open Bypass vs Angioplasty and Stenting of the Lower Extremity Trial (ROBUST): a randomized clinical trial.

IMPORTANCE: To our knowledge, there is no level 1 evidence comparing open bypass with angioplasty and stenting in TransAtlantic Inter-Societ … ality-of-life questionnaire. RESULTS: The trial is actively enrolling participants. At the time of writing, 29 patients have been enrolled; most are male (60%) and white (65%). CONCLUSIONS AND RELEVANCE: Providing level 1 evidence, ROBUST may help to establish guidelines for the treatment of superficial femoral artery lesions, eliminate unnecessary proc …

Fretting and corrosion in modular-neck total hip arthroplasty femoral stems.

BACKGROUND: During total hip arthroplasty, use of a modular femoral neck on a stemmed implant allows optimization of neck anteversion, lengt … radiographs had positive MRI findings consistent with adverse local tissue reaction. At the time of writing, seven patients had undergone revision arthroplasty. Intraoperatively, tissue staining with tissue and bone necrosis and pseudotumor formation were observed in all revision cases. Histological analysis confirmed the presence of metal-on-metal synovi …

The clinical profile of students attending informal schools in three rural governorates in upper Egypt: a community-based study.

BACKGROUND: Combating poverty and illiteracy represents the cornerstone for promoting health among Egyptian children; yet, drop out from the elementary education is a major problem facing stakeholders in Egyptian governorates. To tackle this problem, many projects were implemented such as reading and writing classes, and Girls Education Initiatives (GEIs). OBJECTIVES: The aim of the study was to construct a clinical and laboratory database for students attending the Girls Education Initiative schools in Upper Egypt. PARTICIPANTS AND METHODS: This cross-sectional study was carried out by invo…

Use of a soluble epoxide hydrolase inhibitor as an adjunctive analgesic in a horse with laminitis.

HISTORY: A 4-year old, 500 kg Thoroughbred female horse diagnosed with bilateral forelimb laminitis and cellulitis on the left forelimb beca … ing and after t-TUCB administration. No new episodes of laminitis have been noted up to the time of writing (120 days following treatment). CONCLUSIONS: Inhibition of sEH with t-TUCB was associated with a significant improvement in pain scores in one horse with laminitis whose pain was refractory to the standard of care therapy. No adverse effects were n …

The impact of functional limitations on long-term outcomes among African-American and white women with breast cancer: a cohort study.

OBJECTIVES: We examined the impact of functional limitations and functional decline during the first year following breast cancer diagnosis … 5% CI 1.13 to 1.91), difficulty in pushing or pulling large objects (HR=1.34, 95% CI 1.04 to 1.73), writing or handling small objects (HR=1.56, 95% CI 1.00 to 2.44), and walking half a mile (HR=1.60, 95% CI 1.19 to 2.14). Functional limitations and functional decline did not explain racial disparities in the survival of this cohort. Functional decline was …

European Stroke Organization guidelines for the management of intracranial aneurysms and subarachnoid haemorrhage.

BACKGROUND: Intracranial aneurysm with and without subarachnoid haemorrhage (SAH) is a relevant health problem: The overall incidence is abo … performed an extensive literature search from 1960 to 2011 using Medline and Embase. Members of the writing group met in person and by teleconferences to discuss recommendations. Search results were graded according to the criteria of the European Federation of Neurological Societies. Members of the Guidelines Committee of the European Stroke Organization …

Translating health research evidence into policy and practice in Uganda.

BACKGROUND: Uganda experiences a high disease burden of malaria, infectious and non-communicable diseases. Recent data shows that malaria is … onally relevant health research results. The workshops had an impact on the participants' skills in writing policy briefs, participating in the policy review process and entering into dialogue with policy makers. CONCLUSION: The following lessons have been learned: getting health research into policy is feasible but requires few self-motivated individual …

Mixed schwannoma with meningioma - report on 2 cases of unusual tumor with review of literature.

In order to design learning environments that foster students' research skills, one can draw on instructional design models for complex lear … n a broad way), and a research skills task in which students are asked to integrate their skills in writing a research proposal (in order to assess research skills in an integrative manner). Students' motivational outcomes are measured by means of students' autonomous and controlled motivation, and students' amotivation. A pretest-intervention-posttest de …