Результаты поиска

The first Iranian recommendations on prevention, evaluation and management of high blood pressure.

This paper presents the complete report of the first Iranian Recommendations on Prevention, Evaluation and Management of High Blood Pressure … national and international experts participated in discussions and collaborated in decision-making, writing and reviewing the whole report. Multiple subcommittees worked together to review the recent national and international literature on HTN in different areas. We used the evaluation tool that is called "AGREE" and considered a score of > 60% as a high …

Buprenorphine prescribing practices and exposures reported to a poison center--Utah, 2002-2011.

Buprenorphine is an effective medication for the treatment of opioid dependence. Its use has increased in the United States as a result of t … ine from 22 in 2002 to 9,793 in 2011, and a concurrent increase in the annual number of prescribers writing buprenorphine prescriptions from 16 to 1,088. Over the same period, the number of exposures to buprenorphine reported annually to the PCC increased from six to 81. However, comparison of the ratios of buprenorphine exposures to patients and prescrib …

Histopathological patterns of papillary tumour of the pineal region.

BACKGROUND: Generative artificial intelligence (AI) tools are increasingly used for scientific writing, literature synthesis, and peer-review, yet their responsible use requires awareness of hallucinations, fabricated references, confidentiality risks, authorship limitations, and disclosure requirements. OBJECTIVE: To evaluate the perceived impact of a focused educational workshop on knowledge and attitudes toward AI in scientific publishing among participants in an abdominal wall surgery workshop. METHODS: An anonymous pre-post survey study was conducted during the JAWS Workshop 2026 on Art…

The road to commercialization in Africa: lessons from developing the sickle-cell drug Niprisan.

BACKGROUND: Developing novel drugs from traditional medicinal knowledge can serve as a means to improve public health. Yet countries in sub- … and management challenges, have been put forth to explain Niprisan's commercial demise. As of this writing, NIPRD is considering options for another commercial partner to take the drug forward. SUMMARY: Evidence from the Niprisan experience suggests that establishing benefit-sharing agreements, fostering partnerships with established research institutio …

Allograft-prosthetic composite reconstruction of the proximal part of the tibia. An analysis of the early results.

BACKGROUND: Allograft-prosthetic composite reconstruction of the proximal part of the tibia is one option following resection of a skeletal … bone union occurred in nine patients, and partial union occurred in three patients. At the time of writing, no secondary bone-grafting procedures had been required to achieve union, and no revision or removal of the reconstruction had been performed. Rotational or free flaps provided satisfactory wound coverage in all patients. A deep infection occurred …

Ceftobiprole: first cephalosporin with activity against methicillin-resistant Staphylococcus aureus.

Ceftobiprole medocaril is the first member of a new series of advanced cephalosporins with activity against methicillin-resistant Staphyloco … ntravenous administration; recommended dosage regimens have not been approved by the FDA as of this writing. However, based on the Canadian package insert, expected dosage recommendations are 500 mg as a 1-hour intravenous infusion every 12 hours for the treatment of complicated skin and skin structure infections caused by certain gram-positive pathogens, …

Laparoscopic bilateral adrenalectomy: results for 30 consecutive cases.

BACKGROUND: Most patients requiring bilateral adrenalectomy have adrenocorticotropin hormone (ACTH)-dependent Cushing's syndrome. Some of th … operative steroid replacement and appropriate follow-up assessment with an endocrinologist. At this writing, the patients with Cushing's syndrome available for follow-up evaluation continue to receive steroid replacement, and all the pheochromocytoma patients have experienced a documented postoperative biochemical cure. CONCLUSIONS: Laparoscopic bilatera …

Fracture repair: successful advances, persistent problems, and the psychological burden of trauma.

This article is intended to deliver three messages. First, minimally invasive methods of fracture repair are successful; when coupled with a … r musculoskeletal trauma has been reported in the literature to my knowledge as of the time of this writing, nor do orthopaedic studies routinely control for psychological distress when evaluating outcome. Psychological distress after trauma, with its large impact on trauma outcomes, remains a substantial problem that is usually ignored and untreated.

Use of cethromycin, a new ketolide, for treatment of community-acquired respiratory infections.

BACKGROUND: The ketolides are a subclass of macrolides, which were designed specifically to overcome macrolide-resistant respiratory pathoge … e mainly gastrointestinal. There have been no reports of serious hepatotoxicity at the time of this writing. Cethromycin may have other uses in addition to treatment of CAP respiratory infections, including treatment of infections due to Neisseria gonorrhoeae and Chlamydia trachomatis and bioterrorism agents including Bacillus anthracis, Yersinia pestis a …

The effect of thoracoscopic sympathectomy on quality of life and symptom management of hyperhidrosis.

BACKGROUND: Success with thoracoscopic sympathectomy (TS) for hyperhidrosis is 93% to 100%. We wished to determine if hyperhidrosis patients … were very satisfied with shaking hands (9 of 22 no TS patients and 24 of 26 TS patients, p=0.0003); writing (9 of 11 no TS patients and 25 of 26 TS patients, p=0.0001); eating (11 of 22 no TS patients and 25 of 25 TS patients, p=0.0008). TS patients had more sweating on the abdomen (no TS patients, 0.0 and TS patients, 1.75, p=0.0001), on the groin (no TS …

[Revision of failed fracture hemiarthroplasties to reverse total shoulder prosthesis through the transhumeral approach : method incorporating a pectoralis-major-pedicled bone window].

OBJECTIVE: Alleviation of pain, restoration of function and active range of motion. INDICATIONS: Failed posttraumatic shoulder prostheses w … or up to 59 months postoperatively; an additional nine patients were interviewed by telephone or in writing (n=34, average age 68 years [59-82 years], average follow-up 31.5 months [12-59 months]). The preoperative age- and gender-related Constant Score was 17.5% and improved to 63% postoperatively. Range of motion for active elevation and internal rotati …

The use of massive endoprostheses for the treatment of bone metastases.

Purpose. We report a series of 58 patients with metastatic bone disease treated with resection and endoprosthetic reconstruction over a five … thesis in the lower extremity. The mean age at presentation was 62 years (24 to 88). At the time of writing, 19 patients are still alive, 34 patients have died, and 5 have been lost to follow up. Patients were followed up and evaluated using the musculoskeletal society tumour score (MSTS) and the Toronto extremity salvage score (TESS). The mean MSTS was 7 …

Reincentivizing--a new theory of work and work absence.

BACKGROUND: Work capacity correlates weakly to disease concepts, which in turn are insufficient to explain sick leave behavior. With data mainly from Sweden, a welfare state with high sickness absence rates, our aim was to develop an explanatory theory of how to understand and deal with work absence and sick leave. METHODS: We used classic grounded theory for analyzing data from >130 interviews with people working or on sick leave, physicians, social security officers, and literature. Several hundreds of typed and handwritten memos were the basis for writing up the theory. RESULTS: In this p…

Адефовир дипивоксил для лечения дельты цирроза печени.

ЦЕЛЬ: Сообщить о случае, когда адеповир дипивоксил оказывает положительное воздействие на пациентов с дельта-декомпенсированным циррозом печени, который неэффективно лечится ламиводином. КРАСНОЕ РЕЗЮМЕ: 55-летняя женщина с хроническим вирусом гепатита В (ГБВ), антигепатитом - положительный, а вирусом гепатита дельта (ГБВ) - декомпенсированный цирроз печени (показатель B9 ребенка) - ожидает трансплантации печени. В течение этого времени ее лечили ламивудином 100 мг/сутки; однако через 8 месяцев лекарство было остановлено, поскольку оно не произвело вирусного обезвреживания или не вернуло уровни

Совпадение в аннотации оригинала
OBJECTIVE: To report a case suggesting the beneficial effect of adefovir dipivoxyl in patients with delta-related decompensated liver cirrho … the patient became negative for serum HBV-DNA and immunoglobulin M (IgM) antidelta. At the time of writing (20 mo of therapy), the HBV-DNA and IgM antidelta remained negative, whereas hepatitis B surface antigen and circulating HDV-RNA were positive. No adverse effects associated with adefovir were reported, and the Child-Pugh score (A6) had improved. D …

Nanopantography: a new method for massively parallel nanopatterning over large areas.

We report a radically different approach to the versatile fabrication of nanometer-scale preselected patterns over large areas. Standard lit … on of virtually any shape and material nanostructure. Unlike all other focused ion or electron beam writing techniques, this self-aligned method is virtually unaffected by vibrations, thermal expansion, and other alignment problems that usually plague standard nanofabrication methods. This is because the ion focusing optics are built on the wafer.

Managing intraoperative complications in cataract surgery.

PURPOSE OF REVIEW: This article surveys the literature from 2002 and 2003 and addresses a variety of complications that may arise during cat … of disposable instruments is warranted. Though there is no FDA-recognized use, at the time of this writing, for trypan blue dye, it has become the world standard for intraocular staining because of its safety and efficacy. Clear corneal self-sealing incisions are increasingly mainstream and, when properly constructed, are extremely secure. The most signi …

Prophylaxis in elective colorectal surgery: the cost of ignoring the evidence.

INTRODUCTION: Three strategies are used to prevent complications in colorectal surgery: heparin and antibiotics given perioperatively and ab … ected included patient age and sex, diagnosis, the operating surgeon, and the housestaff or surgeon writing the pre- and postoperative orders. Patients who required emergency colorectal surgery were excluded from the study. Antibiotic, heparin and drain prophylaxis was assessed and considered appropriate if prescribed according to the evidence or inapprop …

Adrenal masses in neoplastic patients: the role of laparoscopic procedure.

BACKGROUND: The incidence of complications resulting from fine-needle biopsy of adrenal masses in patients already treated by radical proced … of seven patients with primary lung cancer, and in one patient with previous kidney cancer. At this writing, three patients were disease free and still alive respectively at 3, 5, and 18 months. Three patients died of brain metastases respectively at 16, 36, and 36 months. An adenoma was proved in the other two cases. CONCLUSIONS: Laparoscopic adrenalect …

Kinematic analysis of handwriting movements in patients with obsessive-compulsive disorder.

OBJECTIVES: Basal ganglia dysfunction is supposed to play a part in the pathophysiology of obsessive-compulsive disorder (OCD). A new computer aided technique for the analysis of hand movements, allowing the detection of subtle motor performance abnormalities, was applied in this study of patients with OCD and healthy controls. METHODS: Using a digitising graphic tablet, hand motor performance was studied in 22 unmedicated patients with OCD and compared with 22 healthy controls. All subjects drew superimposed concentric circles with both the right and the left hand, in addition to writing a g…

[Cerebellar hemorrhage in full-term newborn babies].

INTRODUCTION: Cerebellar hemorrhage (CH) has been observed in 5 to 10% of the autopsies done on newborn babies. Since neuroimaging technique … there were learning difficulties with a low intellectual coefficient and problems with reading and writing. In one case there was epilepsy, controlled by use of two antiepileptic drugs. CONCLUSIONS: Half the cases of CH transfontanellar ultrasound is useful in diagnosis. Most patients were managed conservatively. During the clinical course there were ps …