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Measles antibodies in multiple sclerosis patients.

The Authors have assayed in this work the antimeasles antibodies in serum and CSF in subject affected by M.S. and controls. The M.S. patients have been subdivided in two groups with and without immunosuppressive therapy. In 27% out of 48 patients production intrathecal antimeasles antibodies was demonstrated.

Visual field abnormalities in multiple sclerosis.

Visual fields were examined with a tangent screen in 54 patients with multiple sclerosis (MS) or optic neuritis (ON). Visual fields were abnormal in all patients with definite MS, 94% with probable MS and 81% with possible MS. Three-quarters of the MS patients with no history of visual symptoms had abnormal fields. The commonest defect found was an arcuate scotoma. As a diagnostic test of visual pathway involvement in MS, tangent screen examination compares favourably with more sophisticated methods.

Monoclonal gammopathy associated with multiple sclerosis.

A 52-year-old white male with a 26 year history of multiple sclerosis developed a monoclonal gammopathy of the IgA class, with reciprocal depression of normal immunoglobulins. A bone marrow aspirate and biopsy showed a marked increase in plasma cells, many of which appeared immature. These findings fulfilled the diagnostic criteria for multiple myeloma. The association of multiple myeloma with multiple sclerosis may not be coincidental. Mechanisms regarding this association are discussed.

[Visual evoked potentials in multiple sclerosis].

A study was carried out of 32 patients suffering from multiple sclerosis the diagnois of which was quite definite according to Mac Alpine's criteria and which had developed over more than two years. Comparison was made with patient suffering from optic neuritis of a different aetiology and with normal subjects. The method of investigation was dynamic electroretinoencephalography : the visual evoked potentials were investigated after stimulation by white and coloured light before and after adapatation to darkness. The specificity of the results was tested by, firstly, electro-retinogram recordi…

Abnormal brain scans in multiple sclerosis.

A 25 year old man, with a family history of multiple sclerosis in two preceding generations, developed transient sensory changes and incoordination, initially on the left side, and then several months later on the right side in association with an elevated CSF gamma globulin. This was followed by an acute optic neuritis. During the latter episode he developed a positive brain scan which was unaccompanied by any clinical findings explained by a lesion in that area. Cerebral arteriography was normal and the brain scan returned to normal four weeks later, possibly as a result of blood brain barri…

Auditory evoked responses in multiple sclerosis.

The early components of the auditory evoked responses (waves I-V) have been studied in 30 patients with multiple sclerosis. There were abnormalities in 22 patients. All patients with an internuclear ophthalmoplegia and half those with no detectable brainstem abnormality had abnormal responses, although none was clinically deaf.

Stapedius reflex abnormalities in multiple sclerosis.

Thirteen patients suffering from multiple sclerosis were analyzed by a Madsen ZO 70 electroacoustic bridge connected to an electronystagmograph through an impedance adaptor. Threshold, amplitude, decay and difference limen of intensity (DLI) of the stapedius reflex were examined for the frequencies 500, 1 000, 2 000 and 4 000 Hz. The difference between standard audiometric results and stapedius reflex data stresses the value of reflex measurements in assessing brain stem pathology.

Признание и лечение конъюнктурного амиотропического латерального склероза и множественного склероза.

Амиотропический боковой склероз (ALS) и множественный склероз (MS) являются неврологическими расстройствами с различными основополагающими патофизиологическими свойствами, но могут иметь схожие клинические особенности. Сопровождение обоих заболеваний является крайне редким явлением, поскольку, насколько нам известно, в литературе имеется только 46 документально подтвержденных случаев. В докладе по этому делу сообщается о диагнозе ALS у пациента с многолетним опытом работы с MS и показано важное значение расширения дифференциального диагноза и проведения дополнительной экспертизы у пациента с с

Совпадение в аннотации оригинала
Amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS) are neurological disorders with different underlying pathophysiology but can share similar clinical features. Co-occurrence of both diseases is extremely rare with only 46 documented cases in literature to our knowledge. This case report relays the diagnosis of ALS in a patient with a decades'-l…

Pediatric-onset multiple sclerosis in Finland.

INTRODUCTION: Although there are extensive data on multiple sclerosis (MS) in adults, the epidemiology and clinical features of pediatric-onset multiple sclerosis (POMS) in Finland are unknown. SUBJECTS: and methods: Individuals under 18 years of age diagnosed with clinically isolated syndrome (CIS) or MS were identified from the MS registries of Tampere and Helsinki University Hospitals, based on the ICD-10 classification. The data were extracted from the electronic patient records (EPRs) and MS registries. RESULTS: A total of 73 children with CIS were identified. Among these, 34 (47%) were…