Результаты поиска

Timing of antibiotic administration, wound debridement, and the stages of reconstructive surgery for open long bone fractures of the upper and lower limbs.

BACKGROUND: Open fractures of the major long bones are complex limb-threatening injuries that are predisposed to deep infection. Treatment i … ipants with 617 open fractures. Studies were conducted in medical and trauma centres in the USA and Kenya. Where reported, there was a higher proportion of men and a mean age of participants between 30 and 34 years old. Fractures were in the upper and lower limbs in one study, and were tibia fractures in two studies; where reported, these were the resul …

Trends in Causes of Adult Deaths among the Urban Poor: Evidence from Nairobi Urban Health and Demographic Surveillance System, 2003-2012.

What kills people around the world and how it varies from place to place and over time is critical in mapping the global burden of disease a … d levels of disadvantage of slum dwellers in our analysis relative to other population subgroups in Kenya continue to demonstrate appreciable deterioration of key urban health and social indicators, highlighting the need for a deliberate strategic focus on the health needs of the urban poor in policy and program efforts toward achieving international go …

Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.

BACKGROUND: The Global Burden of Disease, Injuries, and Risk Factor study 2013 (GBD 2013) is the first of a series of annual updates of the … Middle East, Europe, and Asia. For men and women, unsafe sex is the leading risk in a corridor from Kenya to South Africa. INTERPRETATION: Behavioural, environmental and occupational, and metabolic risks can explain half of global mortality and more than one-third of global DALYs providing many opportunities for prevention. Of the larger risks, the att …

Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015.

BACKGROUND: Healthy life expectancy (HALE) and disability-adjusted life-years (DALYs) provide summary measures of health across geographies and time that can inform assessments of epidemiological patterns and health system performance, help to prioritise investments in research and development, and monitor progress toward the Sustainable Development Goals (SDGs). We aimed to provide updated HALE and DALYs for geographies worldwide and evaluate how disease burden changes with development. METHODS: We used results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 20

Совпадение в полном тексте источника
… Although many Group 1 causes remained among the leading causes of DALYs, observed levels were often lower than expected on the basis of SDI (eg, lower respiratory infections in Ethiopia, diarrhoeal diseases in Afghanistan, and preterm birth complications in Kenya). … 10.1097/TA.0b013e3182255cb9 59 Rickard JL Ntakiyiruta G Chu KM Associations with perioperative mortality rate at a major referral hospital in Rwanda World J Surg 40 2015 784 790 10.1007/s00268-015-3308-x 26546186 60 Odhiambo FO Beynon CM Ogwang S Trauma-related mortality among adults in rural western Kenya …

Prevalence, classifications and factors associated with sexual dysfunction among adult cancer patients on chemotherapy at the Uganda Cancer Institute, Mbarara.

BACKGROUND: Sexual dysfunction is a social challenge that devastates many people, including cancer patients. However, among the numerous reported side effects of chemotherapy sexual dysfunction is the least studied and reported. The chemotherapeutics used among cancer patients are potential risk factors for the development of sexual dysfunction, and such an understanding of these risk factors can lead to numerous interventions to bypass their effects on sexual activity. OBJECTIVE: The goal of this study was to determine the prevalence, classification and factors associated with sexual dysfunc

Совпадение в полном тексте источника
… In Kenya, 85% of cancer patients had SD, while 65% of these patients had discussed their sexuality with a physician [ 10 ]. … The current prevalence 42.1% is lower than that reported in studies in Kenya (85%) and Denmark, which reported an overall higher prevalence of 60% [ 19 , 26 ]. …

Paediatric formulations of artemisinin-based combination therapies for treating uncomplicated malaria in children.

BACKGROUND: In endemic malarial areas, young children have high levels of malaria morbidity and mortality. The World Health Organization rec … ls were carried out between 2006 and 2015 in sub-Saharan Africa (Benin, Mali, Mozambique, Tanzania, Kenya, Democratic Republic of the Congo, Burkina Faso, and The Gambia). In all three trials, the paediatric and control ACT achieved polymerase chain reaction (PCR)-adjusted treatment failure rates of < 10% on day 28 in the per-protocol (PP) population. F …

Evaluation of a routine point-of-care intervention for early infant diagnosis of HIV: an observational study in eight African countries.

BACKGROUND: In 2017, there were 180 000 estimated new HIV infections in children aged 0-14 years. Without early diagnosis and treatment, hal … dy, we compared service delivery and clinical outcomes in eight countries (Cameroon, Côte d'Ivoire, Kenya, Lesotho, Mozambique, Rwanda, Swaziland, and Zimbabwe), before and after a POC intervention was introduced for EID of HIV. For the baseline, pre-intervention sample, we sampled 30 consecutive tests for HIV-exposed infants who had a documented date o …

Structural and community-level interventions for increasing condom use to prevent the transmission of HIV and other sexually transmitted infections.

BACKGROUND: Community interventions to promote condom use are considered to be a valuable tool to reduce the transmission of human immunodef … or quantitative assessment. The studies were conducted in Tanzania, Zimbabwe, South Africa, Uganda, Kenya, Peru, China, India and Russia, comprising 75,891 participants, mostly including the general population (not the high-risk population). The main intervention was condom promotion, or distribution, or both. In general, control groups did not receive …

Causes of Death Among Stillbirths and Children Aged <5 Years in Africa and South Asia - Child Health and Mortality Prevention Surveillance, Seven Countries, 2016-2024.

PROBLEM/CONDITION: Sub-Saharan Africa and South Asia have the highest rates of stillbirths and rates of death among children aged <5 years, … as with high mortality. During 2016-2024, CHAMPS operated in seven countries (Bangladesh, Ethiopia, Kenya, Mali, Mozambique, Sierra Leone, and South Africa) through population-defined catchment areas. Eligibility required residence in a CHAMPS catchment area for ≥4 months before death or, for children aged <4 months, since birth. Deaths were investigate …

Treatment outcomes in HIV infected patients older than 50 years attending an HIV clinic in Harare, Zimbabwe: A cohort study.

There is a growing number of older people living with HIV (OPLHIV). While a significant proportion of this population are adults growing into old age with HIV, there are also new infections among OPLHIV. There is a lack of data describing the outcomes of OPLHIV who commenced antiretroviral therapy (ART) after the age of 50 years in sub-Saharan Africa. We conducted a cohort study of patients who enrolled in care at Newlands Clinic in Harare, Zimbabwe, at ages ≥50 years between February 2004 and March 2020. We examined demographic characteristics, attrition, viral suppression, immunological and

Совпадение в полном тексте источника
… Retention in care among older adults living with HIV in western Kenya: A retrospective observational cohort study. PLoS ONE. 2018 ; 13 . doi: 10.1371/journal.pone.0194047 29590150 PMC5874021 35 Haas AD , Zaniewski E , Anderegg N , Ford N , Fox MP , Vinikoor M , et al . … Noncommunicable disease burden among HIV patients in care: A national retrospective longitudinal analysis of HIV-treatment outcomes in Kenya, 2003–2013. …

Editorial: Rare hematological malignancies.

Аннотация не предоставлена источником. Откройте карточку для перехода к публикации.

Совпадение в полном тексте источника
… Acknowledgments PP is currently affiliated to the University of Nairobi (Nairobi, Kenya), and the University of Botswana (Gaborone, Botswana). Funding Statement The author(s) declare that no financial support was received for the research and/or publication of this article. …

Climate changes, environment and infection: facts, scenarios and growing awareness from the public health community within Europe.

Climate change is a current global concern and, despite continuing controversy about the extent and importance of causes and of its effects, … Europe are demonstrated by the fact that recent cases of cholera have been imported to Europe from Kenya, where spreading epidemic has been linked to the El Niño phenomenon, originated from the Pacific Ocean. Human migration and damage to health infrastructures from aberrant climate changes could indirectly contribute to disease transmission. Human sus …

Determinants of Adverse Events in Patients with Cancer Who Practiced Self-Medication: A Cross-Sectional Study in Southwestern Uganda.

BackgroundCancer therapies have been the cornerstone in cancer care. Co-morbidities and Adverse Events (AEs) often encourage some patients with cancer to resort to self-medication in search of relief or better symptom management. While self-medication is a key aspect of self-care and may offer some relief, it also poses risks, especially the potential for AEs. Limited data exist in Uganda, particularly at the Mbarara Regional Referral Hospital (MRRH) Cancer Unit, regarding the prevalence and determinants of AEs.ObjectiveTo determine the prevalence and factors associated with AEs among self-med

Совпадение в полном тексте источника
… The prevalence of AEs among patients with cancer was determined based on a similar study conducted in Kenya, which reported a prevalence of 100%. 20 Because of the prevalence 100%, this makes direct statistical computation impractical, a conservative prevalence of 50% was adopted to ensure maximum variability … For instance, a study in Indonesia reported a closely similar prevalence of 80%, suggesting that AEs are common across different anticancer therapies. 24 In Kenya, a study among cervical patients with cancer found a relatively higher prevalence of 100%, 20 while a study in France reported a lower prevalence …

Advancing Hematopoietic Stem Cell Transplantation (HSCT) in Africa: A Pathway to Curing Hematological Disorders.

BackgroundHematopoietic stem cell transplantation (HSCT) offers a curative option for numerous hematological disorders, notably sickle cell disease and thalassemia, which are highly prevalent in Africa. Despite its potential, access to HSCT remains limited due to infrastructural, economic, and socio-cultural challenges across the continent.MethodsThis review synthesizes current literature and reports on the status of HSCT in Africa, analyzing data from existing transplant centers, national registries, and peer-reviewed studies to assess progress, challenges, and prospects for expanding HSCT se

Совпадение в полном тексте источника
… In Nigeria, SCD has a mortality rate of 50‐80%, and in Kenya, about 4.5% are born with sickle cell. Uganda has a high rate of 45%, and Gabon, and Cameroon share a rate of 20%–30% [ 8 ]. … Tenge , “ THE Prevalence OF Sickle Cell Trait Among Adolescents in Bungoma County, Kenya ,” East African Medical Journal 96 , no. 5 ( 2019 ): 2683 – 2691 . 11 T.‐H. Jaing , T.‐Y. Chang , S.‐H. Chen , C.‐W. Lin , Y.‐C. Wen , and C.‐C. …

Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015.

BACKGROUND: Non-fatal outcomes of disease and injury increasingly detract from the ability of the world's population to live in full health, a trend largely attributable to an epidemiological transition in many countries from causes affecting children, to non-communicable diseases (NCDs) more common in adults. For the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015), we estimated the incidence, prevalence, and years lived with disability for diseases and injuries at the global, regional, and national scale over the period of 1990 to 2015. METHODS: We estimated incid

Совпадение в полном тексте источника
… Eight additional subnational assessments were done for Brazil, China, India, Japan, Kenya, Saudi Arabia, South Africa, Sweden, and the USA (methods appendix pp 611–24 ). For this study we present data at the national and territory level. …

Decision-support tools via mobile devices to improve quality of care in primary healthcare settings.

BACKGROUND: The ubiquity of mobile devices has made it possible for clinical decision-support systems (CDSS) to become available to healthca … ndomized trials across varying healthcare contexts in the USA,. India, China, Guatemala, Ghana, and Kenya, met our inclusion criteria. A range of healthcare providers (facility and community-based, formally trained, and lay workers) used digital CDSS. Care was provided for the management of specific conditions such as cardiovascular disease, gastrointes …

Voxelotor in adolescents and adults with sickle cell disease (HOPE): long-term follow-up results of an international, randomised, double-blind, placebo-controlled, phase 3 trial.

BACKGROUND: For decades, patients with sickle cell disease have had only a limited number of therapies available. In 2019, voxelotor (1500 m … acebo-controlled, phase 3 trial done at 60 clinical sites in Canada, Egypt, France, Italy, Jamaica, Kenya, Lebanon, Netherlands, Oman, Turkey, the USA, and the UK. Patients (aged 12-65 years) with confirmed sickle cell disease, a haemoglobin concentration of 5·5-10·5 g/dL at enrolment, and who had between one and ten vaso-occlusive crisis events in the …

School-based interventions for preventing HIV, sexually transmitted infections, and pregnancy in adolescents.

BACKGROUND: School-based sexual and reproductive health programmes are widely accepted as an approach to reducing high-risk sexual behaviour … ts. Five trials were conducted in sub-Saharan Africa (Malawi, South Africa, Tanzania, Zimbabwe, and Kenya), one in Latin America (Chile), and two in Europe (England and Scotland). Sexual and reproductive health educational programmesSix trials evaluated school-based educational interventions.In these trials, the educational programmes evaluated had no d …