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Restless sleep disorder, restless legs syndrome, and periodic limb movement disorder-Sleep in motion!

Sleep-related movement disorders (SRMDs) represent an important part of pediatric sleep disorders. The most common complaint in SRMD is restless sleep at night. Restless sleep is reported in up to 80% of children with restless legs syndrome (RLS) and children with periodic limb movements of sleep (PLMS) disorder (PLMD). However, restless sleep causing daytime behavioral consequences can be seen in children without another apparent condition and has recently been identified as a new independent primary pediatric sleep disorder, called restless sleep disorder (RSD). This study describes these th…

Impact of rapid eye movement sleep behavior disorder and autonomic disorders on Parkinson's disease: a review.

Parkinson's disease (PD) has heterogeneous clinical manifestations and prognoses. It is accompanied by a group of motor and non-motor symptoms ranging from independence to total disability, limiting work and personal care activities. Currently, disease subtype markers for informing prognosis remain elusive. However, some studies have reported an association between rapid eye movement (REM) sleep behavior disorder (RBD) and faster motor and non-motor symptom progression, including autonomic dysfunction and cognitive decline. Moreover, since autonomic dysfunction has been described in idiopathic

Improving Documentation of Impulse Control Disorders at a Movement Disorder Program During the COVID-19 Pandemic.

BACKGROUND AND OBJECTIVES: Impulse control disorders (ICD) are a group of behaviors in Parkinson disease (PD), (compulsive buying, gambling, binge eating, craving sweets, and hypersexuality) that occur in up to 20% of individuals with PD, sometimes with devastating results. We sought to determine the rate of ICD screening based on 2020 quality measures for PD care by the American Academy of Neurology. METHODS: We conducted a quality improvement project to document and improve physician ICD screening in a tertiary movement disorder program. Serial medical records were reviewed for 5 weeks befo

[Central dysregulations as a cause of movement disorders in performance sports? An analysis of movement in sports with reference to functional anatomic and neurophysiologic viewpoints].

Typical orthopaedic findings and typical disturbances of movement in sports point to central dysregulation in motor disturbances in competitive sports compared with the ideal models set up under biomechanical aspects and from the viewpoint of sports practice. Neurophysiological data collected so far confirm this view. The central influence on movement is manifested by a change in peripheral proprioceptive properties, i.e. by a change in the pre-innervation of the musculature. If the musculature is subjected to high strain as in sports aiming at high performance levels, such changes produce an

DHDDS variants in epilepsy and movement disorders: Two novel mutations and an updated literature review.

INTRODUCTION: Recent evidence suggests that dehydrodolichol diphosphate synthase (DHDDS, MIM*608,172) gene variation can cause neurological … cases of developmental epileptic encephalopathy of unknown cause, progressive myoclonus or complex movement disorders, DHDDS gene screening should be considered.

Training Non-Neurologist Healthcare Professionals in the Recognition and Management of Movement Disorders in Malawi.

BACKGROUND: Many patients with neurological disorders in Malawi are seen by non-neurologist healthcare professionals due to the low number of neurologists available in the country. Movement disorders are a growing concern at neurology clinics and patients often present late, having spent years before getting a neurology referral. In line with the WHO's global action plan on improving neurological care, we organized a workshop for non-neurologist healthcare professionals on the clinical overview of common movement disorders. METHODS: The 2-day in-person workshop was held in Blantyre city and i…

A Pioneering 1915 Film on Movement Disorders in Spain: Parkinsonism, Huntington's Disease, and Paradoxical Kinesia.

BACKGROUND: Soon after the advent of cinematography in 1895, neurologists began exploring its use as a permanent record of physical signs and as a teaching aid. We present the first known Spanish film on movement disorders, recorded in 1915. METHODS: We describe and analyze the patients shown in the film within its historical context. RESULTS: The first section of the film is a teaching session in which a fixed camera records the patients and the professor, surrounded by students. It presents 10 patients, including parkinsonian and catatonic patients. In the second section, a mobile camera f…

Improved outcomes for patients with autonomic movement disorders originally evaluated for psychogenic non-epileptiform spells.

BACKGROUND: Patients experiencing autonomic storms related to dysautonomia may present with abnormal movements, including convulsions, tremors, and myoclonus. Due to these nonspecific symptoms, they are often misdiagnosed with functional neurological disorders, including psychogenic non-epileptic spells (PNES), resulting in delayed or inappropriate treatment. METHODS: This cohort study included 17 adult patients who presented to St. Elizabeth's Medical Center's emergency department with abnormal seizure-like activity. Inclusion criteria required non-epileptiform movements, confirmed by negati

Orthodontic considerations for managing patients with functional movement disorders: a narrative review and clinical guide.

BACKGROUND: Functional Movement Disorder (FMD) is a neurological condition involving involuntary movements without structural brain or nerve damage. It can significantly affect the craniofacial region, disrupting facial and oral motor functions and complicating dental and orthodontic care. This narrative review outlines the clinical presentation of FMD, emphasizing its relevance in orthodontics and offering a clinical management guide. FINDINGS: A systematic approach is proposed, detailing strategies from the initial screening visit through active treatment, retention, and post-retention stag

Self-management interventions involving care partners of individuals with neurodegenerative movement disorders: a scoping review.

PURPOSE: This scoping review aims to explore the components of existing self-management interventions involving care partners of individuals with neurodegenerative movement disorders (NMDs). The review seeks to describe the key components, categorize different types and approaches using the PRISMS taxonomy. METHODS: A comprehensive search was conducted in five databases: SCOPUS, CINAHL, MEDLINE, PsycINFO, and Embase. Articles were included if they involved self-management interventions for adult care partners of individuals with NMDs. Data extraction was guided by the PRISMS, TEDSS and TIDieR…

One Side or Two? A Systematic Review of Deep Brain Stimulation Approaches in Movement Disorders.

BACKGROUND: Deep brain stimulation (DBS) is an established treatment for movement disorders such as Parkinson's disease (PD) and essential tremor (ET). However, the decision between unilateral, staged bilateral, or simultaneous bilateral DBS remains controversial, influenced by clinical presentation, patient preferences, and economic factors. OBJECTIVE: The aim was to compare motor score improvements, adverse events (AE), incremental benefits, and progression with unilateral to bilateral procedures and the rationale for second-side surgery. METHODS: This systematic review examined studies on…

Всеобъемлющий и критический обзор с описанием нарушений движения, связанных с инфекцией на основе вируса денге.

ВИД Денге (ДЕНВ) стал серьезной причиной неврологических осложнений, включая нарушения движения, которые относятся к более широкой категории неврологических проявлений, связанных с инфекцией ДЕНВ. Эти расстройства могут иметь серьезные последствия для качества жизни пациентов, особенно в тропических и субтропических районах, где денге эндемичны. Неврологические осложнения ДЕНВ, хотя и менее широко признанные по сравнению с его классическими особенностями (такими, как лихорадка, геморрагические проявления или шок), все чаще поступают сообщения, что оправдывает исчерпывающую разведку.МЕТОДЫ: Мы

Совпадение в аннотации оригинала
BACKGROUND: Dengue virus (DENV) has emerged as a significant cause of neurological complications, including movement disorders, which fall under the broader category of neurological manifestations associated with DENV infection. These disorders can have serious implications for patient's quality of life, especially in tropical and subtropical regions where d…

Deep brain stimulation for movement disorders treatment in Africa: The current status, outcomes, and challenges.

Movement disorders (MDs), a diverse group of neurological conditions characterized by abnormal and involuntary movements, have a profound impact on individuals, families, and healthcare systems. Deep Brain Stimulation (DBS) has emerged as a promising therapeutic intervention, offering relief from symptoms and improved quality of life. By implanting electrodes in specific brain regions and connecting them to a pulse generator, DBS modulates aberrant neural activity underlying these disorders. While DBS has gained recognition globally, its utilization in African countries remains limited. This c…

Response to iron supplementation is similar between boys and girls with pediatric sleep movement disorders.

OBJECTIVES: This study aims to investigate sex differences in response to iron supplementation in children and adolescents suffering from sleep-related movement disorders such as Restless Legs Syndrome (RLS), Periodic Limb Movement Disorder (PLMD), and Restless Sleep Disorder (RSD). METHODS: Data were retrieved and reanalyzed from previous studies involving children with RLS, PLMD, or RSD. The analysis included 54 patients treated with intravenous (IV) ferric carboxymaltose (FCM) and 31 patients treated with oral ferrous sulfate (FS). Demographic, biological, and clinical parameters were comp…

Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders.

The acyl-CoA-binding domain-containing protein 6 (ACBD6) is ubiquitously expressed, plays a role in the acylation of lipids and proteins and … pmental delay/intellectual disability (100%) with significant expressive language impairment (98%), movement disorders (97%), facial dysmorphism (95%) and mild cerebellar ataxia (85%) associated with gait impairment (94%), limb spasticity/hypertonia (76%), oculomotor (71%) and behavioural abnormalities (65%), overweight (59%), microcephaly (39%) and epilepsy (33%). …

Evolution of Movement Disorders in Patients With CLN2-Batten Disease Treated With Enzyme Replacement Therapy.

OBJECTIVES: Neuronal ceroid lipofuscinosis type 2 (CLN2-disease) is an inherited childhood-onset neurodegenerative condition, with classical early features of speech delay, epilepsy, myoclonus, ataxia, and motor regression. This study aimed to better characterize the spectrum of movement disorders in CLN2-disease in a cohort of children receiving enzyme replacement therapy (ERT). METHODS: A cohort of 18 children attending a single center for treatment with cerliponase alfa ERT was systematically assessed using a standardized structured history and a double-scored, video-recorded examination u…

A Screening Tool to Quickly Identify Movement Disorders in Patients with Inborn Errors of Metabolism.

BACKGROUND: Movement disorders are frequent in patients with inborn errors of metabolism (IEMs) but poorly recognized, particularly by nonmovement disorder specialists. We propose an easy-to-use clinical screening tool to help recognize movement disorders. OBJECTIVE: The aim is to develop a user-friendly rapid screening tool for nonmovement disorder specialists to detect moderate and severe movement disorders in patients aged ≥4 years with IEMs. METHODS: Videos of 55 patients with different IEMs were scored by experienced movement disorder specialists (n = 12). Inter-rater agreements were de…