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[Assessment of the use of partogram at the district maternity hospital of commune II in Bamako area].

OBJECTIVE: To estimate the use of the partogram at the district hospital of commune II in Bamako area; to identify the risk factors by pregnant women and her newborn babies ; to appreciate the filling quality of the partogram; to determine the sensibility, the specificity and the predictive worth of the alert line. METHOD: Our study has been conducted at the district hospital of commune II in Bamako area because of his high examination rate. The study was retrospective, analytic and transversal, conducted during 12 months (from first January 2005 to 31 st December 2005). Were considered in th

[Epilepsy and women's life: particularities of their management. Literature review].

Eight in 1,000 people in the world suffer from epilepsy, and 80 % of them are in the developing countries [1]. Sub-Saharan Africa and Latin America have higher median prevalence's 15.4 % and 12.4 %, respectively, compared to the prevalence in Europe, 5.4 %, and in North America, 5-10 % [2]. On this epidemiological inequality overlays a considerable disparity in the quality of care given to people with epilepsy, between developed and developing countries, and rural and urban areas. In this context, one of the most controversial subject regarding epilepsy is the care given to epileptic patients

Post-mortem characterisation of pathogen-specific causes of infection-related deaths in African and south Asian neonates: a prospective, observational, multicentre study.

BACKGROUND: Post-mortem biological investigation of causes of deaths is uncommon in low-income and middle-income countries (LMICs). The prim … overall causal pathway to death in neonates (aged <28 days) across CHAMPS sites in Ethiopia, Kenya, Mali, Mozambique, Sierra Leone, and South Africa in Africa and Bangladesh in south Asia. METHODS: CHAMPS is a prospective, multicentre, multicountry, observational study that is undertaken across 11 sites with defined catchment areas and high mortality …

Child deaths caused by Klebsiella pneumoniae in sub-Saharan Africa and south Asia: a secondary analysis of Child Health and Mortality Prevention Surveillance (CHAMPS) data.

BACKGROUND: Klebsiella pneumoniae is an important cause of nosocomial and community-acquired pneumonia and sepsis in children, and antibiotic-resistant K pneumoniae is a growing public health threat. We aimed to characterise child mortality associated with this pathogen in seven high-mortality settings. METHODS: We analysed Child Health and Mortality Prevention Surveillance (CHAMPS) data on the causes of deaths in children younger than 5 years and stillbirths in sites located in seven countries across sub-Saharan Africa (Ethiopia, Kenya, Mali, Mozambique, Sierra Leone, and South Africa) and s…

Intention to use contraceptives and its correlates among reproductive age women in selected high fertility sub-saharan Africa countries: a multilevel mixed effects analysis.

BACKGROUND: Intention to use contraceptive methods has an overriding importance to better visualize the women's future needs and more likely … 0%, 53.30%, 42.32%, 37.88%, 37.63%, 35.25%, 31.32%, 20.64%, 20.30% in Burkina Faso, Burundi, Niger, Mali, DR. Congo, Nigeria, Angola, Gambia, and Chad respectively. Age; 15-24 (AOR = 3.72, 95% CI, 3.58, 3.86) and 25 - 24 years (AOR = 2.81, 95% CI, 2.74, 2.89), education of women; primary (AOR = 1.16, 95% CI, 1.13, 1.20), and secondary (AOR = 1.32, 95% …

Situational analysis of infant and young child nutrition policies and programmatic activities in the Islamic Republic of Mauritania.

Progress towards reducing mortality and malnutrition among children <5 years of age has been less than needed to achieve related Millennium … n of children <2 years of age in Mauritania as one of the six target countries (Burkina Faso, Chad, Mali, Mauritania, Niger, Senegal). These findings are available to assist countries in identifying inconsistencies and filling gaps in current programming. Between August and November of 2008, key informants responsible for conducting IYCN-related activi …

[Acute catatonic syndrome after neuroleptic malignant syndrome].

We report the case of a young woman who deve-loped catatonic syndrome a few days after neuroleptic mali-gnant syndrome (NMS), arising the problem of the chronology of both affections. A 20-year old woman with an history of bipolar disorder, experienced an acute manic syndrome that made hospitalization necessary. Fourteen days after loxa-pine prescription, the patient developed a NMS (DSM IV criteria) dyskinesia, dysphagia, fever and alteration of cons-ciousness. Hepatic transaminases and muscular enzymes increased. Neuroleptic was immediately interrupted and benzodiazepines (Lorazepam) was sta…

High prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6')-Ib-cr, and qepA among ceftiofur-resistant Enterobacteriaceae isolates from companion and food-producing animals.

Three kinds of plasmid-mediated quinolone resistance (PMQR) determinants have been discovered and have been shown to be widely distributed among clinical isolates: qnr genes, aac(6')-Ib-cr, and qepA. Few data on the prevalence of these determinants in strains from animals are available. The presence of PMQR genes in isolates from animals was determined by PCR amplification and DNA sequencing. The production of extended-spectrum beta-lactamases (ESBLs) and AmpC beta-lactamases in the strains was detected, and their genotypes were determined. The genetic environment of PMQR determinants in selec

Post-mortem investigation of deaths due to pneumonia in children aged 1-59 months in sub-Saharan Africa and South Asia from 2016 to 2022: an observational study.

BACKGROUND: The Child Health and Mortality Prevention Surveillance (CHAMPS) Network programme undertakes post-mortem minimally invasive tiss … nd Dec 31, 2022, in the CHAMPS Network across six countries in sub-Saharan Africa (Ethiopia, Kenya, Mali, Mozambique, Sierra Leone, and South Africa) and one in South Asia (Bangladesh). A standardised approach of MITS was undertaken on decedents within 24-72 h of death. Diagnostic tests included blood culture, multi-organism targeted nucleic acid ampli …

Trends in Prevalence of Tobacco Use by Sex and Socioeconomic Status in 22 Sub-Saharan African Countries, 2003-2019.

IMPORTANCE: Tobacco companies have shifted their marketing and production to sub-Saharan African countries, which are in an early stage of t … e in smoking was achieved among female participants in 15 countries: Cameroon, Namibia, Mozambique, Mali, Liberia, Nigeria, Burundi, Tanzania, Malawi, Kenya, Rwanda, Zimbabwe, Ethiopia, Burkina Faso, and Zambia. For both sexes, the prevalence of tobacco use and the decrease in prevalence of tobacco use were higher among less-educated individuals and in …

Association of Genetic Variants With Primary Open-Angle Glaucoma Among Individuals With African Ancestry.

IMPORTANCE: Primary open-angle glaucoma presents with increased prevalence and a higher degree of clinical severity in populations of Africa … , Britain, Cameroon, Saudi Arabia, Brazil, the Democratic Republic of the Congo, Morocco, Peru, and Mali from 2003 to 2018. Individuals with primary open-angle glaucoma had open iridocorneal angles and displayed glaucomatous optic neuropathy with visual field defects. Elevated intraocular pressure was not included in the case definition. Control indivi …

[Postoperative nocardiosis caused by Nocardia otitidiscaviarum: pitfalls and delayed diagnosis].

Nocardiosis is an uncommon infection, which is exceptionally present as a postoperative event. A case of postoperative pulmonary and cerebro-meningeal infection caused by Nocardia otitidiscaviarum after a leg amputation in a diabetic patient is reported. Diagnosis has been delayed and the clinical, radiological and microbiological causes of this delay are assessed from a quality of care management point of view. Recommendations are proposed regarding physicians' role and optimized microbiological procedures for recognition of slowly growing nocardial strains.

[Molecular epidemiology of large bacterial endemics in Sub-Saharan Africa].

Over the past decades, the differentiation of bacterial strains for epidemiological purposes had been based on conventional phenotypic chara … membrane proteins of Neisseria meningitidis allowed the differentiation of the strains isolated in Mali according to the period of isolation. Thus, the endemic strains of A serotype were distinguished from those belonging to the same serotype, which were responsible for the 1994 epidemic. Several molecular methods were applied to the typing of Vibrio …

Hepatoblastoma regional trends: dynamic SDI & joinpoint regression analysis.

BACKGROUND: Hepatoblastoma (HB), the most common pediatric primary liver cancer, accounts for 80% of childhood liver malignancies but only 1% of all pediatric cancers. Approximately 90% of cases occur in children under five years old, with 20-40% of patients presenting with distant metastases at diagnosis. Surgical resection is critical, but only 50-60% of tumors are completely resectable initially; unresectable or highly invasive cases require liver transplantation, highlighting the disease's severe clinical and economic burden. Despite regional disparities in incidence and mortality, the glo…

Безопасность, реактивогенность и иммуногенность шимпанзе аденовирусной вакцины от Эболы у взрослых людей в Африке: случайная, слепая, контролируемая плацебо, стадия 2.

В 2014 году эпидемия вируса Эбола в Заире ускорила разработку вакцины для этого вируса. Мы стремились оценить безопасность, реактивогенность и иммуногенность одной дозы моновалента, рекомбинанта, шимпанзе аденовируса типа 3, венерированной вакциной от гликопротеина в Заире (ChAD3-EBO-Z) у взрослых. МЕТОДЫ: На этом этапе 2 в учебных центрах в Камеруне, Мали, Нигерии и Сенегале были проведены выборочные и контролируемые испытания с участием наблюдателей. Здоровые взрослые (≥18 лет) были произвольно назначены с веб-системой (1:1; процедура сведения к минимуму с учетом возраста, пола, центра) для

Совпадение в аннотации оригинала
BACKGROUND: The 2014 Zaire Ebola virus disease epidemic accelerated vaccine development for the virus. We aimed to assess the safety, reacto … : This phase 2, randomised, observer-blind, controlled trial was done in study centres in Cameroon, Mali, Nigeria, and Senegal. Healthy adults (≥18 years) were randomly assigned with a web-based system (1:1; minimisation procedure accounting for age, gender, centre) to receive ChAd3-EBO-Z (day 0), or saline placebo (day 0) and ChAd3-EBO-Z (month 6). Th …

[Microeconomic evaluation of a mass preventive immunisation campaign against meningococcal meningitis and yellow fever in Senegal in 1997].

Large epidemics of group A meningococcal meningitis occurred in 1995 and 1996 in several countries of the Sub-Saharan Africa zone known as t … -to-6 weeks following the moment the threshold is reached. In this context of epidemics, notably in Mali, and in front of the risk of resurgence of yellow fever, the Ministry of Health of Senegal decided to conduct mass preventive immunization campaigns in 1997 against meningo- coccal meningitis and yellow fever in the districts located in the eastern …

The incidence and antimicrobial resistance of Shigella-attributable diarrhoea in young children in low-income and middle-income countries from the multicountry Enterics for Global Health (EFGH) Shigella Surveillance Study: a prospective, facility-based hybrid surveillance study.

BACKGROUND: Shigella is a leading cause of dysentery and watery diarrhoea in low-income and middle-income countries (LMICs) with consequence … illance study conducted from June 21, 2022, to Aug 25, 2024, across seven countries: Kenya, Malawi, Mali, The Gambia, Bangladesh, Pakistan, and Peru. Children aged 6-35 months presenting at selected health-care facilities with acute diarrhoea (three or more abnormally loose or watery stools in the last 24-h period lasting less than 14 days) were enroll …

Impact of acute malaria on pre-existing antibodies to viral and vaccine antigens in mice and humans.

Vaccine-induced immunity depends on long-lived plasma cells (LLPCs) that maintain antibody levels. A recent mouse study showed that Plasmodium chaubaudi infection reduced pre-existing influenza-specific antibodies--raising concerns that malaria may compromise pre-existing vaccine responses. We extended these findings to P. yoelii infection, observing decreases in antibodies to model antigens in inbred mice and to influenza in outbred mice, associated with LLPC depletion and increased susceptibility to influenza rechallenge. We investigated the implications of these findings in Malian children …

[Cervico-facial traumatic injuries at the Donka national hospital of the teaching hospital of Conakry].

The Cervico-Facial Traumatic Injuries (CFTI) can entrain complications and serious aesthetic and functional sequella. The objectives of this study were to determine the frequency of CFTI, to describe the clinical forms and to evaluate the treatment. It was a prospective study conducted from February to July 2010 in the National Donka hospital of the Teaching Hospital of Conakry. The study concerned 265 patients, who benefited a treatment and reevaluated. The young adults aged between 21-30 years were the most affected (38.49%). 74.34 % were men and 25.66 % were females with a sex ratio of 2.9.