Orthodontic treatment of a child with Crigler-Najjar syndrome type I using tacrolimus following liver transplantation.

The present study reports the orthodontic treatment of a child with Crigler-Najjar syndrome type I following a liver transplant and administration of tacrolimus (1 mg/day). Tacrolimus (FK506) is fundamental to immunosuppression following transplantation. The child exhibited Class II division 1 malocclusion. The treatment option was to use a Herbst appliance for seven months and a fixed appliance (straight wire) for 12 months.