Surgical neurology · 2009
Multiple dynamic cavernous malformations in a girl: long-term follow-up.
Клинический случайСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Chen Liang, Zhao Yao, Chen Zheng, Tee May, Mao Ying, Zhou Liang-Fu
Аннотация
BACKGROUND: Cavernous malformations have generally been viewed as fairly benign vascular lesions with low potential for causing massive hemorrhage.
CASE DESCRIPTION: We present an interesting case of multiple CMs, several of which were formed de novo and exhibited aggressive biological behavior resulting in recurrent episodes of intracranial hemorrhage over a 10-year period. This case illustrates a dynamic and aggressive form of CMs. Recent advances in our understanding of the molecular pathogenesis of CMs implicate genetics as an important pathogenic factor, which is the most likely etiology of this patient's presentation.
CONCLUSION: Special challenges exist in managing young children with multiple, highly aggressive CMs.
CASE DESCRIPTION: We present an interesting case of multiple CMs, several of which were formed de novo and exhibited aggressive biological behavior resulting in recurrent episodes of intracranial hemorrhage over a 10-year period. This case illustrates a dynamic and aggressive form of CMs. Recent advances in our understanding of the molecular pathogenesis of CMs implicate genetics as an important pathogenic factor, which is the most likely etiology of this patient's presentation.
CONCLUSION: Special challenges exist in managing young children with multiple, highly aggressive CMs.
Предметные рубрики MeSH
Angiography, Digital SubtractionCalcinosisCerebellar NeoplasmsCerebellumCerebral HemorrhageChildChild, PreschoolDominance, CerebralFemaleFollow-Up StudiesFrontal LobeGait AtaxiaHemangioma, Cavernous, Central Nervous SystemHumansInfantMagnetic Resonance ImagingNeoplasm Recurrence, LocalNeoplasms, Multiple PrimaryNeurologic ExaminationNeuronavigationOccipital LobeParietal LobePostoperative ComplicationsReoperationTomography, X-Ray Computed