Movement disorders clinical practice · 2025
Status Dystonicus in Children: Is it more Common than we Realize?
СтатьяНазвание и аннотация: Перевод в очереди
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Al Azri Nadia, Vogt Lindsey M, LeBlanc-Millar Andrea, Breitbart Sara, Fasano Alfonso, Ibrahim George M, Gorodetsky Carolina
Аннотация
BACKGROUND: Status dystonicus (SD) is the most severe form of dystonia, affecting predominantly children. SD is thought to be rare, but the incidence is unknown.
OBJECTIVE: We aimed to: (1) assess the number of admissions involving SD (2) describe complications/intensive care unit (ICU) transfers, and (3) evaluate whether these changed with implementation of a treatment pathway.
METHODS: We retrospectively collected data for patients with SD admitted to the Hospital for Sick Children from January 2020 to June 2024.
RESULTS: We identified 92 admissions among 48 patients with SD (20/year). Genetic/metabolic dystonia accounted for 45%. Triggers for SD were seen in 82%. The complication rate was 39%, with 27%/19% of individuals requiring ICU care pre/post-pathway, respectively.
CONCLUSIONS: SD is common, especially in children with genetic/metabolic dystonia, often with identifiable triggers. More data are required to understand the impact of a clinical pathway. Awareness is necessary to mitigate complications.
OBJECTIVE: We aimed to: (1) assess the number of admissions involving SD (2) describe complications/intensive care unit (ICU) transfers, and (3) evaluate whether these changed with implementation of a treatment pathway.
METHODS: We retrospectively collected data for patients with SD admitted to the Hospital for Sick Children from January 2020 to June 2024.
RESULTS: We identified 92 admissions among 48 patients with SD (20/year). Genetic/metabolic dystonia accounted for 45%. Triggers for SD were seen in 82%. The complication rate was 39%, with 27%/19% of individuals requiring ICU care pre/post-pathway, respectively.
CONCLUSIONS: SD is common, especially in children with genetic/metabolic dystonia, often with identifiable triggers. More data are required to understand the impact of a clinical pathway. Awareness is necessary to mitigate complications.