Developmental cognitive neuroscience · 2024

Quantifying brain development in the HEALthy Brain and Child Development (HBCD) Study: The magnetic resonance imaging and spectroscopy protocol.

Протокол клинического исследованияСтатьяПоддержка NIH: внешняя программаНазвание и аннотация: Перевод в очереди

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Dean Douglas C, Tisdall M Dylan, Wisnowski Jessica L, Feczko Eric, Gagoski Borjan, Alexander Andrew L, Edden Richard A E, Gao Wei, Hendrickson Timothy J, Howell Brittany R, Huang Hao, Humphreys Kathryn L, Riggins Tracy, Sylvester Chad M, Weldon Kimberly B, Yacoub Essa, Ahtam Banu, Beck Natacha, Banerjee Suchandrima, Boroday Sergiy, Caprihan Arvind, Caron Bryan, Carpenter Samuel, Chang Yulin, Chung Ai Wern, Cieslak Matthew, Clarke William T, Dale Anders, Das Samir, Davies-Jenkins Christopher W, Dufford Alexander J, Evans Alan C, Fesselier Laetitia, Ganji Sandeep K, Gilbert Guillaume, Graham Alice M, Gudmundson Aaron T, Macgregor-Hannah Maren, Harms Michael P, Hilbert Tom, Hui Steve C N, Irfanoglu M Okan, Kecskemeti Steven, Kober Tobias, Kuperman Joshua M, Lamichhane Bidhan, Landman Bennett A, Lecour-Bourcher Xavier, Lee Erik G, Li Xu, MacIntyre Leigh, Madjar Cecile, Manhard Mary Kate, Mayer Andrew R, Mehta Kahini, Moore Lucille A, Murali-Manohar Saipavitra, Navarro Cristian, Nebel Mary Beth, Newman Sharlene D, Newton Allen T, Noeske Ralph, Norton Elizabeth S, Oeltzschner Georg, Ongaro-Carcy Regis, Ou Xiawei, Ouyang Minhui, Parrish Todd B, Pekar James J, Pengo Thomas, Pierpaoli Carlo, Poldrack Russell A, Rajagopalan Vidya, Rettmann Dan W, Rioux Pierre, Rosenberg Jens T, Salo Taylor, Satterthwaite Theodore D, Scott Lisa S, Shin Eunkyung, Simegn Gizeaddis, Simmons W Kyle, Song Yulu, Tikalsky Barry J, Tkach Jean, van Zijl Peter C M, Vannest Jennifer, Versluis Maarten, Zhao Yansong, Zöllner Helge J, Fair Damien A, Smyser Christopher D, Elison Jed T, HBCD MRI Working Group

Аннотация

The HEALthy Brain and Child Development (HBCD) Study, a multi-site prospective longitudinal cohort study, will examine human brain, cognitive, behavioral, social, and emotional development beginning prenatally and planned through early childhood. The acquisition of multimodal magnetic resonance-based brain development data is central to the study's core protocol. However, application of Magnetic Resonance Imaging (MRI) methods in this population is complicated by technical challenges and difficulties of imaging in early life. Overcoming these challenges requires an innovative and harmonized approach, combining age-appropriate acquisition protocols together with specialized pediatric neuroimaging strategies. The HBCD MRI Working Group aimed to establish a core acquisition protocol for all 27 HBCD Study recruitment sites to measure brain structure, function, microstructure, and metabolites. Acquisition parameters of individual modalities have been matched across MRI scanner platforms for harmonized acquisitions and state-of-the-art technologies are employed to enable faster and motion-robust imaging. Here, we provide an overview of the HBCD MRI protocol, including decisions of individual modalities and preliminary data. The result will be an unparalleled resource for examining early neurodevelopment which enables the larger scientific community to assess normative trajectories from birth through childhood and to examine the genetic, biological, and environmental factors that help shape the developing brain.

Предметные рубрики MeSH

Child Child, Preschool Female Humans Infant Infant, Newborn Male Brain Child Development Longitudinal Studies Magnetic Resonance Imaging Magnetic Resonance Spectroscopy Neuroimaging Prospective Studies Multicenter Studies as Topic

Quantifying brain development in the HEALthy Brain and Child Development (HBCD) Study: The magnetic resonance imaging and spectroscopy protocol.

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Аннотация

Предметные рубрики MeSH