The Journal of veterinary medical science · 2003
Experimental infection of recent field isolates of feline herpesvirus type 1.
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Hamano Masataka, Maeda Ken, Mizukoshi Fuminori, Une Yumi, Mochizuki Masami, Tohya Yukinobu, Akashi Hiroomi, Kai Kazushige
Аннотация
Two field isolates of feline herpesvirus type 1 (FHV-1) designated as 00-015 and 00-035, were obtained from cats diagnosed as feline viral rhinotracheitis (FVR) in Japan. To analyze the character of recent FHV-1, these two isolates and our laboratory strain C7301 were inoculated experimentally to specific-pathogen-free cats. Although all cats showed typical FVR symptoms, more severe clinical symptoms were observed on cats infected with the isolates 00-015 and 00-035 compared with those of C7301-infected cats. Severe ocular lesions including conjunctivitis were found in the cats infected with the isolates, indicating that the recent FHV-1 has a potential to induce severe FVR symptoms including ocular lesions.