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DOI 10.1227/ons.0000000000001420

Медицинская библиотека · Operative neurosurgery (Hagerstown, Md.) · 2024

Have We Made Advancements in Optimizing Surgical Outcomes and Enhancing Recovery for Patients With High-Risk Adult Spinal Deformity Over Time?

Passias Peter G, Passfall Lara, Tretiakov Peter S, Das Ankita, Onafowokan Oluwatobi O, Smith Justin S, Lafage Virginie, Lafage Renaud, Line Breton, Gum Jeffrey, Kebaish Khaled M, Than Khoi D, Mundis Gregory, Hostin Richard, Gupta Munish, Eastlack Robert K, Chou Dean, Forman Alexa, Diebo Bassel, Daniels Alan H, Protopsaltis Themistocles, Hamilton D Kojo, Soroceanu Alex, Pinteric Raymarla, Mummaneni Praveen, Kim Han Jo, Anand Neel, Ames Christopher P, Hart Robert, Burton Douglas, Schwab Frank J, Shaffrey Christopher, Klineberg Eric O, Bess Shay, International Spine Study Group

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Аннотация

BACKGROUND AND

OBJECTIVES

The spectrum of patients requiring adult spinal deformity (ASD) surgery is highly variable in baseline (BL) risk such as age, frailty, and deformity severity. Although improvements have been realized in ASD surgery over the past decade, it is unknown whether these carry over to high-risk patients. We aim to determine temporal differences in outcomes at 2 years after ASD surgery in patients stratified by BL risk.

METHODS

Patients ≥18 years with complete pre- (BL) and 2-year (2Y) postoperative data from 2009 to 2018 were categorized as having undergone surgery from 2009 to 2013 [early] or from 2014 to 2018 [late]. High-risk [HR] patients met ≥2 of the criteria: (1) ++ BL pelvic incidence and lumbar lordosis or SVA by Scoliosis Research Society (SRS)-Schwab criteria, (2) elderly [≥70 years], (3) severe BL frailty, (4) high Charlson comorbidity index, (5) undergoing 3-column osteotomy, and (6) fusion of >12 levels, or >7 levels for elderly patients. Demographics, clinical outcomes, radiographic alignment targets, and complication rates were assessed by time period for high-risk patients.

RESULTS

Of the 725 patients included, 52% (n = 377) were identified as HR. 47% (n = 338) had surgery pre-2014 [early], and 53% (n = 387) underwent surgery in 2014 or later [late]. There was a higher proportion of HR patients in Late group (56% vs 48%). Analysis by early/late status showed no significant differences in achieving improved radiographic alignment by SRS-Schwab, age-adjusted alignment goals, or global alignment and proportion proportionality by 2Y (all P > .05). Late/HR patients had significantly less poor clinical outcomes per SRS and Oswestry Disability Index (both P < .01). Late/HR patients had fewer complications (63% vs 74%, P = .025), reoperations (17% vs 30%, P = .002), and surgical infections (0.9% vs 4.3%, P = .031). Late/HR patients had lower rates of early proximal junctional kyphosis (10% vs 17%, P = .041) and proximal junctional failure (11% vs 22%, P = .003).

CONCLUSION

Despite operating on more high-risk patients between 2014 and 2018, surgeons effectively reduced rates of complications, mechanical failures, and reoperations, while simultaneously improving health-related quality of life.

Для цитирования: Passias Peter G, Passfall Lara, Tretiakov Peter S, Das Ankita, Onafowokan Oluwatobi O, Smith Justin S, Lafage Virginie, Lafage Renaud, Line Breton, Gum Jeffrey, Kebaish Khaled M, Than Khoi D, Mundis Gregory, Hostin Richard, Gupta Munish, Eastlack Robert K, Chou Dean, Forman Alexa, Diebo Bassel, Daniels Alan H, Protopsaltis Themistocles, Hamilton D Kojo, Soroceanu Alex, Pinteric Raymarla, Mummaneni Praveen, Kim Han Jo, Anand Neel, Ames Christopher P, Hart Robert, Burton Douglas, Schwab Frank J, Shaffrey Christopher, Klineberg Eric O, Bess Shay, International Spine Study Group. Have We Made Advancements in Optimizing Surgical Outcomes and Enhancing Recovery for Patients With High-Risk Adult Spinal Deformity Over Time?. Operative neurosurgery (Hagerstown, Md.). 2024. DOI: 10.1227/ons.0000000000001420.

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