Newer glomerular diseases.

Three recently described primary, non-immune-mediated glomerular diseases are reviewed. These three distinct forms of glomerulopathy include collagen type III glomerulopathy, fibronectin glomerulopathy, and lipoprotein glomerulopathy. The three entities are characterized pathologically by the glomerular deposition of substances either produced or trapped in the renal glomerulus. All three diseases usually present with proteinuria or nephrotic syndrome, and are slowly progressive. Collagen type II and fibronectin glomerulopathy are familial diseases, and lipoprotein glomerulopathy may be familial or sporadic.