Phenomenon of adjustment of brain rhythm coordination in healthy adolescents and with traumatic brain injury: An important marker of post-traumatic brain restoration.

The recently proposed concept of cross-communication of physiologically significant cortical rhythms has expanded existing understanding of the cooperative dynamics of brain waves during changes in the functional state of the body, demonstrating the importance of identifying not only changes in the amplitudes of dominant rhythms or individual paired interactions, but also focusing on the coordination of non-dominant rhythmic processes. Based on this concept, we have discovered an important phenomenon demonstrating an adjustment of the cooperative dynamics of brain waves during deep sleep in young patients (adolescents) with traumatic brain injury and in a control group of healthy volunteers. However, during wakefulness, significant differences in the coordination of brain rhythms were observed between these two groups. Since deep sleep is crucial for physical restoration, tissue regeneration, and immune system strengthening, we suppose that return of normal cooperative dynamics of brain waves during deep sleep is a manifestation of physiological regenerative processes and may serve as an important diagnostic marker for the effectiveness of post-traumatic therapy.