Acta neurologica Scandinavica · 1998
Hypoplasia, stenosis and other alterations of the vertebral artery: does impaired blood rheology manifest a hidden disease?
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Oder B, Oder W, Lang W, Marschnigg E, Deecke L
Аннотация
OBJECTIVES: The clinical relevance of abnormal vessel findings in the posterior circulation is still a matter of controversy.
PATIENTS AND METHODS: We compared 48 patients displaying sonographic abnormalities of one vertebral artery, i.e., vertebral artery hypoplasia in 24 cases, stenosis in 13 cases, plaques in 11 cases, with 25 healthy subjects in terms of whole blood viscoelasticity and plasma viscosity.
RESULTS: All patients with stenosis and plaques suffered from clinical signs and symptoms of ischemic cerebrovascular disease, predominantly in the posterior circulation. Free of acute clinical symptoms were 5 of the 24 patients with hypoplasia. Highly statistically significant differences in blood viscoelasticity were found between the patients and the healthy subjects. As regards differences between the groups, whole blood viscoelasticity was most impaired in stenosis, shear resistance was significantly higher in stenosis compared to hypoplasia. Symptom-free patients with one-sided vertebral artery hypoplasia had a significantly better, nearly normal blood rheology at a low shear rate (10/s), compared to clinically symptomatic patients with hypoplasia.
CONCLUSION: The results of the present study offer some evidence that altered hemorheology may be associated with symptomatic vertebrobasilar occlusive disease.
PATIENTS AND METHODS: We compared 48 patients displaying sonographic abnormalities of one vertebral artery, i.e., vertebral artery hypoplasia in 24 cases, stenosis in 13 cases, plaques in 11 cases, with 25 healthy subjects in terms of whole blood viscoelasticity and plasma viscosity.
RESULTS: All patients with stenosis and plaques suffered from clinical signs and symptoms of ischemic cerebrovascular disease, predominantly in the posterior circulation. Free of acute clinical symptoms were 5 of the 24 patients with hypoplasia. Highly statistically significant differences in blood viscoelasticity were found between the patients and the healthy subjects. As regards differences between the groups, whole blood viscoelasticity was most impaired in stenosis, shear resistance was significantly higher in stenosis compared to hypoplasia. Symptom-free patients with one-sided vertebral artery hypoplasia had a significantly better, nearly normal blood rheology at a low shear rate (10/s), compared to clinically symptomatic patients with hypoplasia.
CONCLUSION: The results of the present study offer some evidence that altered hemorheology may be associated with symptomatic vertebrobasilar occlusive disease.