Clinical features of cerebral schistosomiasis, especially in cerebral and hepatosplenomegalic type.

Clinical features of cerebral schistosomiasis type (CST) and hepatosplenic schistosomiasis type (HST), and typical cases of each type were presented. Results of comparative study of clinical symptoms of both type among three countries in Japan, China and Philippines were discussed. CST in Japan and HST in the Philippines showed unique profiles when they were compared with those in other two countries. Although the reason for the difference is not clear, it might be determined by infection burden, pathogenicity of schistosome and/or immune response to the parasite antigen in human hosts.