Arquivos de neuro-psiquiatria · 2004
[Anatomical and functional abnormalities of central nervous system in autistic disorder: a MRI and SPECT study].
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Machado Marbene Guedes, Oliveira Hélio Araújo, Cipolotti Rosana, Santos Clara Augusta Garcia Moreno, de Oliveira Emanoella Faro, Donald Robert Moraes, Krauss Miriam Peres de Oliveira
Аннотация
We present a study of anatomical and functional abnormalities of central nervous system (CNS) from patients with autistic disorder (AD); magnetic resonance imaging (MRI) and single photon emission computed tomography (SPECT) were used for the investigation. The population studied was composed of 24 patients, 15 (62.5%) males and 9 (17.5%) females, mean age 9 years. MRI was performed in all patients and SPECT was performed in 19 patients; 75% (n=18) of patients had anatomical abnormalities and all patients that realized SPECT had functional abnormalities. Anatomical abnormalities were preferentially noted in corpus callosum (25%), septum pellucidum (15.63%), cerebral ventricles (12.55%), cerebellum (9.38%), temporal lobes (6.25%), occipital lobes (6.25%) and hippocampus (6.25%). Functional abnormalities predominated in frontal lobes (53.13%), temporal lobes (28.13%), parietal lobes (15.63%) and basal ganglia (3.13%). However, anatomical and functional abnormalities of CNS are not priorities for diagnosis, which should have always clinical validation.