The Clinical journal of pain · 2012
Bisphosphonates for pain management in children with benign cartilage tumors.
Клинический случайСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Winston Mark J, Srivastava Tarak, Jarka Dale, Alon Uri S
Аннотация
OBJECTIVES: Cochrane meta-analyses have shown significant benefit in bone pain from bisphosphonate therapy in adults with bone diseases such as multiple myeloma, Paget disease, breast and prostate cancer. Our aim was to assess if bisphosphonate treatment could alleviate severe pain in children with Ollier disease and hereditary multiple exostoses that are refractory to standard analgesics.
METHODS: We report our clinical experience with bisphosphonate therapy in 2 children with cartilage tumors, one with Ollier disease, and the other with hereditary multiple exostoses.
RESULTS: We found bisphosphonate therapy to be helpful for pain relief and improving overall ability to carry out daily activities.
DISCUSSION: One can consider bisphosphonate therapy in children with Ollier disease and hereditary multiple exostoses who have debilitating pain that is refractory to standard analgesic treatment.
METHODS: We report our clinical experience with bisphosphonate therapy in 2 children with cartilage tumors, one with Ollier disease, and the other with hereditary multiple exostoses.
RESULTS: We found bisphosphonate therapy to be helpful for pain relief and improving overall ability to carry out daily activities.
DISCUSSION: One can consider bisphosphonate therapy in children with Ollier disease and hereditary multiple exostoses who have debilitating pain that is refractory to standard analgesic treatment.