Geriatric syndromes in women living with HIV.

PURPOSE OF REVIEW: To describe the current research on geriatric syndromes in women with HIV (WWH) and their potential clinical implications.

RECENT FINDINGS: Geriatric syndromes are multifactorial age-related changes that are associated with functional decline. In those without HIV, many geriatric syndromes have a higher prevalence in women. In those with HIV, there are important sex differences in frailty trajectories and sarcopenia. WWH demonstrate an increased risk for osteoporosis and cognitive decline compared to men and to women without HIV. Urinary incontinence and social isolation are also prevalent in WWH and impact quality of life. Several of these geriatric syndromes are modified by the menopausal transition in WWH.

SUMMARY: Research is needed to identify the predictors of geriatric syndrome development and progression in WWH. These findings could inform timing of screening or intervention strategies for aging WWH.